Changes in Lab and Ultrasonography After Endoscopic Varisceal Treatment

• Conditions: Liver Cirrhosis
• Interventions: Diagnostic Test: Liver function tests (ALT,AST,ALBUMIN,BILIRUBIN,INR,PC,CBC); Device: biannual ultrasonography

• Registration Number: NCT03269786
• Lead Sponsor: Assiut University

Brief Summary

laboratory and ultrasongraphicc changes after endoscopical varices treatment

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-08-27
• Study First Submitted QC: 2017-08-31
• Study First Posted: 2017-09-01
• Status Verified: 2018-10
• Last Update Submitted: 2018-10-07
• Last Update Posted: 2018-10-09
• Study Start: 2018-11-01
• Primary Completion: 2019-11-01
• Study Completion: 2019-11-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• patients with liver cirrhosis and portal hyprtension with esophagel varisces

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Exclusion Criteria

• 1. Patients with heart failure or renal failure 2. patients with COPD 3. Patients with hepato cellular carcinoma and portal vein thrombosis 4. Pregnant

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
cirrhotic patients with esophagel varisces	Liver function tests (ALT,AST,ALBUMIN,BILIRUBIN,INR,PC,CBC)	Endoscopic band ligation or injection scelerotheraby will be done for all patients
cirrhotic patients with esophagel varisces	biannual ultrasonography	Endoscopic band ligation or injection scelerotheraby will be done for all patients

Primary Outcome Measures

Name	Time	Method
Changes in liver function tests	6 months	Liver function tests (ALT, AST, bilirubin,Albumin,Cbc,Prothrombin time,INR ) level (expected to be lower after endoscopic varisceal treatment; (ex
Ultrasonographic changes	6 months	{ portal vein diameter , portal vein velocity and flow direction, volume flow in portal vein , congetive index, spleen size.(expected to be chnged after endoscopic varisceal treatment

Trial Locations

Locations (1)

Assiut University; 🇪🇬 Assuit, Egypt