Prevalence and Associated Factors of Functional Gastrointestinal Disorders Among Children

Not yet recruiting

• Conditions: Functional Gastrointestinal Disorders

• Registration Number: NCT05605405
• Lead Sponsor: Assiut University

Brief Summary

The definition of Functional Gastrointestinal Disorders (FGIDs) has changed over time from the absence of organic disease to a stress-related or psychiatric disorder to a motility disorder, and with Rome III, to a disorder of GI functioning, then Rome iv in 2016 defined FGIDs as : disorders of gut-brain interaction. It is a group of disorders classified by GI symptoms related to any combination of the following: motility disturbance, visceral hypersensitivity,altered mucosal and immune function, altered gut microbiota, and altered central nervous system (CNS) processing. FGIDs are observed in infants and young children worldwide with variable frequency related studies done in variable places around the worled show the following results : the prevalence of FGIDs in Chinese infants and young children is 27.3%.and 40 % in south american infants and 30 % of african infants and 35.1 % of infants presented to tertiary care hospital in Istunbul.Turkey.

Detailed Description

The etiology of these disorders remains uncertain and thought to be due to subtle alteration of the normal development or maladaptive behavioral response to a variety of internal or external stimuli .As a group of disorders; FGIDs in young children are a major challenge to the already overstretched pediatric gastroenterology services across the world .Infants and young children with FGIDs visit medical professionals more frequently and experience poor quality of life . In addition, FGIDs in infancy are linked with detrimental repercussions such as maternal depression, poor infant and mother bonding,and poor physical growth .

Study Timeline

• Study First Submitted: 2021-09-22
• Status Verified: 2022-10
• Study First Submitted QC: 2022-10-29
• Last Update Submitted: 2022-10-29
• Study First Posted: 2022-11-04
• Last Update Posted: 2022-11-04
• Study Start: 2022-12
• Primary Completion: 2023-09
• Study Completion: 2023-12

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 269

Inclusion Criteria

• Age group 1 to 18 years old

Exclusion Criteria

• Age group bwlow 1 year and above 18 years

Having other git problem as :

• GIT bleeding
• H pylori infection
• Cow's milk protein allergy or IBD or any other symptoms suggestive to organic GI disease

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The associated factors	50 weeks	Demographic and social
Prevalence of functional gastrointestinal disorders among children attending gastrointerology clinic of Assuit University Children Hospital	50 weeks	A number will calculated