NL-OMON46831撤回不适用
Qualification of imaging methods to assess cancer drug induced interstitial lung disease (ImageILD) - EORTC-1658-IG
European Organisation for Research in Treatment of Cancer (EORTC)0 个研究点目标入组 5 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 发起方
- 入组人数
- 5
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •* Age * 18 years
- •* WHO performance status 0-2
- •* Life expectancy > 6 months
- •* Proven cancer diagnosis in a patient actively undergoing systemic anticancer
- •* New onset symptoms (e.g. cough, fever, dyspnoea, and hypoxia) at any
- •time during or within 4 weeks of the last dose of anti-cancer treatment
- •* New onset radiological (CXR or CT) abnormalities within the lungs at any
- •time during or within 4 weeks of the last dose of anti-cancer treatment
- •(e.g. diffuse lung changes, infiltrative opacification in the periphery of the
- •lung or ground glass changes) with a locally reviewed diagnosis of DIILD as
- •the most likely explanation for the radiological abnormalities.
- •* Treatment for DIILD planned (e.g. drug withdrawal, interruption +/-
- •supportive therapy including corticosteroids, oxygen, bronchodilators etc.).
- •Treatment with antibiotics, anticoagulants etc. is permitted pending results
- •of investigations for differential diagnoses.
- •* Able to undergo pulmonary function tests (at a minimum spirometry and
- •gas transfer (DLCO))
- •* Patients enrolled on other anti-cancer investigational trials are permitted
- •at investigator discretion
- •* Informed written consent obtained according to ICH/GCP, and
- •national/local regulations
- •* Women of child bearing potential (WOCBP) must have a negative serum (or
- •urine) pregnancy test within 14 days before study registration
排除标准
- •* Primary lung tumor greater than 3cm
- •* Lung metastatic lesion > 2cm or greater than 5 metastases
- •* Claustrophobia, or inability to undergo non-contrast CT examination
- •* Known or suspected non-drug related ILD (e.g. lung abnormalities due to
- •other causes such as occupational exposure)
- •* Previous thoracic lobectomy
- •* Clinical, radiological or microbiological evidence of active lower respiratory
- •tract infection
- •* Currently active, clinically significant heart disease, such as uncontrolled
- •class 3 or 4 congestive heart failure defined by the New York Heart
- •Association Functional Classification
- •* Any medical, psychological, sociological or geographical condition that
- •could affect participation in the study and compliance with the study
研究者
相似试验
尚未招募
不适用
Defining optimal imaging strategies for diagnosis, treatment, and treatment evaluation of chordomas and chondrosarcomas of the axial skeletoBone tumor10040778NL-OMON54229eids Universitair Medisch Centrum40
已完成
不适用
Development of the tumor-specific imaging technique on targeting amino acid transporterHealthy subjects, Brain tumor patientsJPRN-UMIN000015271Osaka City University Graduate School of Medicine40
已完成
不适用
Functional imaging for advanced cancer treatmentAdvanced cancerJPRN-UMIN000005128Biomedical Imaging Research Center, University of Fukui100
招募中
不适用
Development of imaging biomarkers based on tumor microenvironment for personalized treatment planning of peritoneal metastasis/recurrence in advanced gastric cancerNeoplasmsKCT0007302Soon Chun Hyang University240
招募中
不适用
Accuracy of diagnostic imaging techniques in patients with a suspected fracture-related infectioNL-OMON46568niversitair Medisch Centrum Groningen200