Use of ST250 to Reconstruct Lateral Tongue Defects

Completed

• Conditions: Tongue Neoplasms

• Registration Number: NCT06988449
• Lead Sponsor: Cairo University

Brief Summary

To assess the use of SupraThel 250 for mucosal reconstruction in the Head \& Neck region. The membrane is applied to reconstruct lateral tongue defects . healing of the mucosa and regaining of normal tongue movement and speech are assessed postoperatively.

Detailed Description

Lateral tongue defects are usually treated using radial fore-arm free grafts which require a prolonged hospital stay with higher morbidity rates. It also entails the need of multiple rehabilitation and remodeling porcdures of the transplnted flap to enable intelligible speech and tongue function.

Study Timeline

• Study Start: 2022-07-01
• Primary Completion: 2025-01-30
• Study Completion: 2025-03-30
• Status Verified: 2025-05
• Study First Submitted: 2025-05-16
• Study First Submitted QC: 2025-05-16
• Last Update Submitted: 2025-05-16
• Study First Posted: 2025-05-23
• Last Update Posted: 2025-05-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

• lateral tunge defects (postoncologic resection)

Exclusion Criteria

• radio / chemotherapy
• pregnant/ breastfeeding women

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain score	5 days

Trial Locations

Locations (1)

MarienHospital; 🇩🇪 Stuttgart, Baden-Wurttemberg, Germany