Laser Assisted Nonsurgical Periodontal Treatment

Not Applicable

• Conditions: Chronic Periodontitis
• Interventions: Device: Gracey Curettes; Device: Ultrasonics

• Registration Number: NCT03387371
• Lead Sponsor: Bezmialem Vakif University

Brief Summary

Periodontitis is a chronic inflammatory disease caused by mixed infections with the subgingival microbiota being organized as a biofilm that, if untreated, may result in breakdown of the periodontal tissues in susceptible individuals. Evidence from intervention studies shows that mechanical root debridement significantly improves periodontal health by halting the progression of periodontal tissue breakdown. In order to improve effectiveness and efficacy of the removal of the subgingival biofilm, Er:YAG laser therapy has recently been recommended as an alternative to conventional scaling procedures.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-07-18
• Status Verified: 2017-11
• Study First Submitted: 2017-11-07
• Study First Submitted QC: 2017-12-29
• Last Update Submitted: 2017-12-29
• Study First Posted: 2018-01-02
• Last Update Posted: 2018-01-02
• Primary Completion: 2018-01-20
• Study Completion: 2018-01-20

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 38

Inclusion Criteria

Greater than 25 years, Clinical diagnosis of moderate to advanced chronic periodontitis, Pocket depth ≥ 5 mm or clinic attachment level ≥ 4 mm at least in two interproximal areas (not on the same tooth), Along with very good oral hygiene scores (GI≤1and PI≤1), At least 4 teeth in each quadrant, Teeth with subgingival plaque sample is collected has no restoration or prothesis

Exclusion Criteria

Periodontal treatment ( root planning or surgical periodontal treatment) had done before, Systemic disease that could influence the outcome of periodontal therapy, Prophylaxis regime mandatory during periodontal treatment, Use of any drug that could influence the outcome of periodontal therapy, Use of antibiotics within the last 3 months, Use of anti-inflammatory drugs within the last 3 months, Use of removable prothesis Pregnancy, lactation or use of hormone contraceptives, Smoking

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Ultrasonics & Gracey Curettes & Laser	Gracey Curettes	Scaling and root planning is done with ultrasonics, gracey curettes and Er:YAG laser in 24 hours with two visits.
Ultrasonics & Gracey Curettes	Ultrasonics	Scaling and root planning is done with ultrasonics and gracey curettes in 24 hours with two visits.
Ultrasonics & Gracey Curettes	Gracey Curettes	Scaling and root planning is done with ultrasonics and gracey curettes in 24 hours with two visits.

Primary Outcome Measures

Name	Time	Method
Subgingival Plak Sample 1	1. month	quantitative changes on red complex bacterias
Clinic Attachment Level 6	6. month	to measure the Clinic Attachment Level of all teeth
Subgingival Plak Sample 3	3. month	quantitative changes on red complex bacterias
Probing Pocket Depth 3	3. month	to measure the probing pocket depth of all teeth
Clinic Attachment Level 3	3. month	to measure the Clinic Attachment Level of all teeth
Subgingival Plak Sample 6	6. month	quantitative changes on red complex bacterias
Probing Pocket Depth 6	6. month	to measure theProbing Pocket Depth of all teeth

Secondary Outcome Measures

Name	Time	Method
Bleeding On Probing 3	3. month	to record the Bleeding On Probing of all teeth
Plak Index 3	3. month	to record the plak index of all teeth
Plak Index 6	6. month	to record the plak index of all teeth
Bleeding On Probing 6	6. month	to record the Bleeding On Probing of all teeth