Clinical and Microbiologic Effects of Nonsurgical Periodontal Treatment Combined With an Erbium: Yttrium Aluminium Garnet Laser
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Chronic Periodontitis
- Sponsor
- Bezmialem Vakif University
- Enrollment
- 38
- Primary Endpoint
- Subgingival Plak Sample 1
- Last Updated
- 8 years ago
Overview
Brief Summary
Periodontitis is a chronic inflammatory disease caused by mixed infections with the subgingival microbiota being organized as a biofilm that, if untreated, may result in breakdown of the periodontal tissues in susceptible individuals. Evidence from intervention studies shows that mechanical root debridement significantly improves periodontal health by halting the progression of periodontal tissue breakdown. In order to improve effectiveness and efficacy of the removal of the subgingival biofilm, Er:YAG laser therapy has recently been recommended as an alternative to conventional scaling procedures.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Greater than 25 years, Clinical diagnosis of moderate to advanced chronic periodontitis, Pocket depth ≥ 5 mm or clinic attachment level ≥ 4 mm at least in two interproximal areas (not on the same tooth), Along with very good oral hygiene scores (GI≤1and PI≤1), At least 4 teeth in each quadrant, Teeth with subgingival plaque sample is collected has no restoration or prothesis
Exclusion Criteria
- •Periodontal treatment ( root planning or surgical periodontal treatment) had done before, Systemic disease that could influence the outcome of periodontal therapy, Prophylaxis regime mandatory during periodontal treatment, Use of any drug that could influence the outcome of periodontal therapy, Use of antibiotics within the last 3 months, Use of anti-inflammatory drugs within the last 3 months, Use of removable prothesis Pregnancy, lactation or use of hormone contraceptives, Smoking
Outcomes
Primary Outcomes
Subgingival Plak Sample 1
Time Frame: 1. month
quantitative changes on red complex bacterias
Clinic Attachment Level 6
Time Frame: 6. month
to measure the Clinic Attachment Level of all teeth
Subgingival Plak Sample 3
Time Frame: 3. month
quantitative changes on red complex bacterias
Probing Pocket Depth 3
Time Frame: 3. month
to measure the probing pocket depth of all teeth
Clinic Attachment Level 3
Time Frame: 3. month
to measure the Clinic Attachment Level of all teeth
Subgingival Plak Sample 6
Time Frame: 6. month
quantitative changes on red complex bacterias
Probing Pocket Depth 6
Time Frame: 6. month
to measure theProbing Pocket Depth of all teeth
Secondary Outcomes
- Bleeding On Probing 3(3. month)
- Plak Index 3(3. month)
- Plak Index 6(6. month)
- Bleeding On Probing 6(6. month)