Validation of New Tools for the Assessment of Cognitive Functions and Connectivity Network in Hypertensive Patients

Neuromed IRCCS1 site in 1 country160 target enrollmentFebruary 2015

ConditionsHypertension Cognitive Impairment

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Hypertension
Sponsor: Neuromed IRCCS
Enrollment: 160
Locations: 1
Primary Endpoint: Cognitive abilities measured by validated neuropsychological test battery (Montreal Cognitive Assessment test, Verbal Fluency test,learning of couple words, Stroop test)
Status: Completed
Last Updated: 4 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The relationship among hypertension, aging and cognitive decline is complex and not completely understood. Purpose of this project will be evaluating early markers of cognitive deterioration in patients with arterial hypertension. In particular, this cross-sectional observational study will be articulated in three phases:

Neuropsychological evaluation of general cognitive abilities
Identification and measurement of specific biomarker levels
Correlation among hypertension, cognitive abilities and biomarkers.

Registry

clinicaltrials.gov

Start Date

February 2015

End Date

December 2020

Last Updated

4 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Neuromed IRCCS

Responsible Party

Principal Investigator

Giuseppe Lembo

MD, PhD

Neuromed IRCCS

Eligibility Criteria

Inclusion Criteria

•Males or females diagnosed with arterial hypertension between 40 and 65 years of age;
•Written informed consent prior to enrollment in the study.

Exclusion Criteria

•Precedent acute myocardial infarction (AMI);
•Previous stroke and/or transient ischemic attack (TIA);
•Previous or concomitant neurologic or psychiatric pathologies;
•Neurologic or psychiatric pharmacological therapy.

Outcomes

Primary Outcomes

Cognitive abilities measured by validated neuropsychological test battery (Montreal Cognitive Assessment test, Verbal Fluency test,learning of couple words, Stroop test)

Time Frame: 18 months