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Terapia PEG-Interferone alfa 2B+Ribavirina versus terapia PEG-Interferone alfa 2B + Ribavirina+ Terapia ormonale sostitutiva (TOS) nella prevenzione della progressione della fibrosi epatica nell’epatite cronica HCV positiva in eta' post-menopausale - ND

Conditions
Women in post-menopause with Chronic HCV positive hepatitis
MedDRA version: 9.1Level: SOCClassification code 10019805Term: Hepatobiliary disorders
Registration Number
EUCTR2008-001260-36-IT
Lead Sponsor
AZIENDA OSPEDALIERA POLICLINICO DI MODENA
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Authorised-recruitment may be ongoing or finished
Sex
Female
Target Recruitment
Not specified
Inclusion Criteria

Women age from menopause to 70 years old
Chronic HCV positive hepatitis
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

Age > 70
Suspected hypersensitivity to Interferon, PEG-Interferon or Ribavirin

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Main Objective: Reduction of fibrosis progression and liver cirrhosis in post-menopausal women with chronic HCV positive hepatitis;Secondary Objective: Efficacy of hormone replacement therapy + Interferon + Peg-Interferon + Rivabirin in post-menopausal women compared to pre-menopausal women;Primary end point(s): Reduction of fibrosis progression and liver cirrhosis in post-menopausal women with chronic HCV positive hepatitis
Secondary Outcome Measures
NameTimeMethod
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