A study to evaluate the safety and efficacy of ex vivo expanded autologous gamma/delta T cell infusion following zoledronic acid sensitization in patients who received radiotherapy for bone metastases.
Not Applicable
- Conditions
- Patients with bone metastatic cancer
- Registration Number
- JPRN-UMIN000000628
- Lead Sponsor
- niversity of Tokyo, Graduate School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 10
Inclusion Criteria
Not provided
Exclusion Criteria
Patients who have: out-of-controlled infections, active autoimmune diseases, serious complications, other cancers, active enteritis, and symptoms of fibroid lung or interstitial pneumonia; who have received continuous systemic steroids; who are pregnant, to be pregnant, or nursing mothers, and whom principle investigator or co-investigator judged to be inappropriate to participate in this study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Adverse events
- Secondary Outcome Measures
Name Time Method Antitumor effects on the metastatic foci and primary lesion; Time to progression; Improvement of tumor-related markers, and immunological parameters.