MedPath

The Integrated Population (I-POP) Health Trial

Not Applicable
Active, not recruiting
Conditions
Diabetes
Chronic Kidney Diseases
Obesity
Hypertension
Chronic Disease
Interventions
Other: Usual Care
Other: I-POP + CHW navigation
Registration Number
NCT04761016
Lead Sponsor
Baylor Research Institute
Brief Summary

The primary aim of this study is to determine whether community health worker (CHW) navigation improves outcomes of chronic disease and chronic disease risk factors in a low-income, primarily ethnic minority population when combined with an evidence-based population health model as compared to usual care after 10 months.

Detailed Description

The I-POP+CHW participants will be paired with a CHW at baseline to assist with navigation for 10-months between health and wellness services in the selected zip codes: 75210, 75215, 75216, 75217, 75223, or 75227. Participants will receive a multi-level intervention utilizing the current I-POP Health model that includes: 1) Access to health services (including oral health), 2) Access to clinical prevention services, 3) Access to education and facilities to increase physical activity and improved nutrition choices, and 4) Scheduled visits with CHWs for education and navigation. Individuals will complete study measures at baseline, 6-months, and 10-months.

The control group participants will receive access to the same I-POP Health resources without CHW navigation until the end of 10-months (delayed CHW navigation). The current usual care model is outlined below (section 2.3) Participants will complete study measures at baseline, 6-months, and 10-months timepoints. Upon completion of 10-months measures, these individuals will be assigned a CHW and receive delayed navigation.

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
202
Inclusion Criteria
  • Age 18 years or older
  • Ability to alter diet and/or physical activity
  • Willing to participate in a 10-month study
  • Resident of selected zip codes: 75210, 75215, 75216, 75217, 75223, or 75227
  • Not having utilized BSW HWC membership services within the past 12 months
  • Not planning to move outside of the selected zip code area within the next 6 months
Exclusion Criteria
  • Below the age of 18 years
  • Unable or unwilling to alter diet and/or physical activity
  • Not willing to participate in a 10-month study
  • Not resident of local selected zip codes: 75210, 75215, 75216, 75217, 75223, or 75227
  • Currently using or have used BSW HWC membership services within the past 12 months
  • Planning to move outside of the selected zip code area within the next 6 months

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
ControlUsual CareControl group participants will receive access to the same I-POP Health resources without CHW navigation until the end of 10-months (delayed CHW navigation). The current usual care model is outlined. Participants will complete study measures at baseline, 6-months, and 10-months timepoints. Upon completion of 10-months measures, these individuals will be assigned a CHW and receive delayed navigation.
I-POP CHW InterventionI-POP + CHW navigationI-POP+CHW participants will be paired with a CHW at baseline to assist with navigation for 10-months between health and wellness services in the selected zip codes: 75210, 75215, 75216, 75217, 75223, or 75227. Participants will receive a multi-level intervention utilizing the current I-POP Health model that includes: 1) Access to health services (including oral health), 2) Access to clinical prevention services, 3) Access to education and facilities to increase physical activity and improved nutrition choices, and 4) Scheduled visits with CHWs for education and navigation. Individuals will complete study measures at baseline, 6-months, and 10-months.
Primary Outcome Measures
NameTimeMethod
HbA1c10-months

Finger stick blood measure (%)

Allostatic load6-months

A composite score of 10 biomarkers to measure chronic stress and health outcomes. The biomarkers are BMI, waist-to-hip ratio, HDL, TC/HDL ratio, triglycerides, HbA1c, SBP, DBP, C-reactive protein, and cortisol. For each marker a value of 1 will be assigned if that exceed the third quartile except for HDL where a value of 1 will be assigned if lower than first quartile; otherwise a score of zero will be assigned. \[scale: Count of risk factors. May be dichotomized as high risk = 6 to 10, low risk=0 to 5\].

Cortisol6-months

4mL saliva collected fasting in the morning. \[Scale: measured in a continuous scale. Normal range 0.007 - 0.115 ug/dL. Value exceeded the normal range indicates higher level of stress.\]

C-Reactive protein6-months

4mL saliva collected fasting in the morning. \[Scale: measured in a continuous scale. Normal range 25 pg/mL - 1600 pg/mL. Value exceeded the normal range indicates higher level of inflammation.\]

Body mass index10-months

Weight in pounds (lbs) divided by height in inches (in) squared and multiplying by a conversion factor of 703

Waist - to - Hip ratio10-months

Waist circumference (centimeters) divided by circumference of hips (centimeters)

Lipids10-months

Finger stick blood measure collected fasting via fingerstick (mg/dL)

Blood pressure10-months

Stadiometer used to measure systolic and diastolic pressures to nearest 1 mm Hg

Secondary Outcome Measures
NameTimeMethod
Physical activity10-months

Measured by self report questionnaire \[type, frequency, and time completed in minutes\]

Diet10-months

Measured by self report Dietary Screening questionnaire (DSQ). \[scale: dietary nutrients will be calculated on a continuous scale based on NHANES guideline. Score: 0 to any positive value. A score above or below the threshold based on 2000 calories per day would indicate worse outcome.\]

Services utilization10-months

Measured by self-report survey. \[scale: count the number visits at healthcare or wellness centers. A higher score would indicate better utilization.\]

Social determinants10-months

Measured by self-report survey

Perceived stress10-months

Measured by Perceived Stress Scale (PSS-10) \[scale: high risk=40, moderate risk=20, low risk=0\]

Medication use10-months

Measured by self-report survey

Trial Locations

Locations (1)

Baylor Research Institute

🇺🇸

Dallas, Texas, United States

© Copyright 2025. All Rights Reserved by MedPath