ACTRN12613000512729招募中1 期
A pilot study to evaluate safety and feasibility of administrating prophylactic doses of zoledronic acid to prevent symptomatic osteonecrosis following chemotherapy for acute lymphoblastic leukemia and lymphoma in children and adolescents.
Sydney Children's Hospital Network0 个研究点目标入组 10 人开始时间: 2013年5月8日最近更新:
适应症
试验速览
- 阶段
- 1 期
- 状态
- 招募中
- 发起方
- 入组人数
- 10
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Non-randomised trial
- 主要目的
- Prevention
入排标准
- 年龄范围
- 5 Years 至 16 Years（—）
- 性别
- All
入选标准
- •1)Diagnosis of Acute lymphoblastic leukemia or lymphoblastic lymphoma
- •2)Age more than 10 years for Zoledronic acid intervention(group1)
- •3)Age between 5yr-10 yr and able to have MRI without general anaesthetic for investigations (group2)
排除标准
- •1)25 hydroxy vitamin D< 50 nmol/L
- •2)Hypocalcemia corrected for albumin
- •3)Prior bisphosphonate use
- •4)Estimated glomerular filtration rate (GFR) <35ml/min/1.73 m2 at screening based on Schwartz formula
- •5)Diagnosis of active uveitis
- •6)History of primary bone disease (osteogenesis imperfecta, idiopathic juvenile osteoporosis, rickets/osteomalacia)
- •7)Unable to have MRI without general anaesthesia
研究者
相似试验
终止
不适用
A pilot study investigating the safety and feasibility of embolising the left gastric artery to aid rapid weight-loss in morbidly obese patients awaiting elective surgery.Diet and Nutrition - ObesityObesityACTRN12621000095864I-MED Radiology Network1
进行中（未招募）
1 期
Identification of the sentinel lymph node (SLN) in patients with colon carcinoma.Colon carcinomaEUCTR2019-003179-20-NLMeander Medical Centre10
招募中
1 期
A pilot study of patients with oligometastases from breast cancer treated with stereotactic ablative body radiosurgery in combination with the anti-PD-1 antibody MK-3475.Metastatic Breast Cancer (1-5 metastases)Cancer - BreastCancer - BoneACTRN12614001181695Peter MacCallum Cancer Centre15
招募中
不适用
A pilot study to assess the safety and feasibility of fluorescent sentinel lymph node identification in colon carcinoma using Indocyanine green.NL-OMON24349Meander Medical Centre, Department of Surgery10
进行中（未招募）
1 期
Identification of the sentinel lymph node (SLN) in patients with colon carcinoma.Colon carcinomaEUCTR2021-006796-41-NLMeander Medical Centre5