Prokinetics to alter the position of the gastric acid pocket in Gastro Esophageal Reflux Disease
- Conditions
- Gastroesophageal reflux diseaseheartburn10017977
- Registration Number
- NL-OMON33309
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
GERD patients with a hiatal hernia
- 18-65 years
- esophagitis and/or pH-metry with an acid exposure of > 4,5%
- hiatal hernia as seen on endoscopy or barium swallow of > 3 cm
GERD patients without a hiatal hernia
- 18-65 years
- esophagitis and/or pH-metry with an acid exposure of > 4,5%
- no hiatal hernia or a hiatal hernia < 2 cm as seen on endoscopy or barium swallow
Exclusion Criteria
Exclusion criteria
- surgery of the gastrointestinal tract other then appendectomy
- use of medication that interfere with gastrointestinal motility
- inability to stop the use of proton pump inhibitors for one week
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method