NL-OMON21579已完成不适用
ASsessment of Platelet function in patients Recovering from severe INfection
Vrije Universiteit Medisch Centrum Amsterdam0 个研究点目标入组 97 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 97
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •In order to be eligible to participate in the main-trial, a subject must meet all of the following criteria:
- •Primary clinical diagnosis of pneumonia
- •Primary clinical diagnosis of invasive urinary tract infection
- •Primary clinical diagnosis of cutaneous infection
- •18 years or older on the date of hospital presentation
- •Hospitalization for at least 24 hours
- •Having received at least 1 dose of antibiotics within 48 hours of admission.
- •In order to be eligible to participate in the sub-study, a subject must meet all of the following criteria:
- •Primary clinical diagnosis of pneumonia
- •Primary clinical diagnosis of invasive urinary tract infection
- •Primary clinical diagnosis of cutaneous infection
- •18 years or older on the date of hospital presentation
- •Hospitalization for at least 24 hours
- •Having received at least 1 dose of antibiotics within 48 hours of admission
- •Known stable cardiovascular disease. Stable cardiovascular disease defined as: coronary artery disease, peripheral vascular disease, or previous myocardial infarction (>12 months).
- •Chronic usage of 80 mg of non-enteric coated acetylsalicylic acid once daily in the
排除标准
- •A potential subject who meets any of the following criteria will be excluded from participation in the main-trial:
- •-Active metastatic cancer (c.q. malignancy)
- •-Allergy to salicylate
- •-Platelet count <120*109/l
- •-History of non-traumatic major bleeding
- •-Known bleeding diathesis
- •-Conditions which require antiplatelet therapy
- •-Usage of antiplatelet therapy
- •-Surgery 1 month prior to diagnosis
- •-Currently pregnant
- •-Chronic usage of medication which are known to influence
- •platelet function other than antibiotics (e.g. NSAID’s, tirofiban, eptifibatide, abciximab, SSRI’s, clomipramine, amitriptyline, dipyridamole, verapamil, diltiazem , ginkgo biloba, ginseng, & St John’s wort)
- •A potential subject who meets any of the following criteria will be excluded from participation in the sub-study:
- •-Active metastatic cancer (c.q. malignancy)
- •-Platelet count <120*109/l
- •-History of non-traumatic major bleeding
- •-Known bleeding diathesis
- •-Surgery 1 month prior to diagnosis
- •-Currently pregnant
- •-Cardiovascular event < 12 months prior
- •-Chronic usage of medication which are known to influence
- •platelet function other than antibiotics or aspirin (e.g. NSAID’s, tirofiban, eptifibatide, abciximab, SSRI’s, clomipramine, amitriptyline, dipyridamole, verapamil, diltiazem , ginkgo biloba, ginseng, & St John’s wort)
研究者
相似试验
已完成
不适用
Platelet rEactivity in patieNts with DrUg eLUting stent and balancing risk of bleeding and ischeMic eventPatients with ACS or elective indications undergoing PCI with drug-eluting stent implantation.JPRN-UMIN000020332Toho University Ohashi Medical Center6,422
招募中
不适用
Platelet reactivity over time in patients undergoing vascular surgeryantiplatelet therapy10003216atherosclerosisNL-OMON46079niversitair Medisch Centrum Utrecht50
招募中
不适用
Platelet dysfunction at trauma patientsD65Disseminated intravascular coagulation [defibrination syndrome]DRKS00025434BG Klinikum Bergmannstrost Halle gGmbH700
已完成
4 期
ASsesment of Platelet function and Inhibition in patients Recovering from severe INfectionHeart attack10011082Acute myocardial infarctionNL-OMON50157Vrije Universiteit Medisch Centrum97
进行中（未招募）
1 期
Evaluation of platelet activity in patients recovering from a severe infectioHyperaggregability of thrombocytes triggered by severe infection (i.e. pneumonia or invasive urinary tract infection or a cutaneous infection).EUCTR2016-004303-32-NLVU university medical center62