Activation of the Sphingosine-1-phosphate (S1P) to S1P1 Receptor Subtype (S1PR1) Axis in Patients With Interstitial Cystitis (IC) Pain : Identification of Potential Relevant Biomarkers
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 21
- 试验地点
- 1
- 主要终点
- Change From Baseline in Pain Scores on the Visual Analog Scale at 6 months
研究概览
简要总结
For each patient in the study, blood, and pain scores will be collected to look for markers for pain, at the start of treatment and 6 months after surgery of treatment.
详细描述
The study is investigator-initiated, prospective, study. There will be no change in care.
Patients who have had a diagnosis of IC made by cystoscopy and hydrodistension and still have pain will be recruited for this study.
Patients will have blood samples taken at the visit they sign the consent form and 6 months later.
The study staff will call and remind the patient of their 6 month visit.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •18-70 years of age
- •Patients must be able to provide written informed consent.
- •Diagnosis of Interstitial Cystitis documented by provider
排除标准
- •age <18 or >70 years of age
结局指标
主要结局
Change From Baseline in Pain Scores on the Visual Analog Scale at 6 months
时间窗: 3 months
S1PR1 levels in PBLs can discriminate patients with Interstitial Cystitis pain and patients with other types of pain.
次要结局
未报告次要终点
研究者
Eugen C. Campian, MD
Principal Investigator
St. Louis University