Effect of Ilex latifolia Thunb. extract on the adults who complained of memory deterioration for the Efficacy and Safety; A 8week, Randomized, Double-blind, Placebo-Controlled Clinical Trial
Not Applicable
Completed
- Conditions
- Mental and behavioral disorders
- Registration Number
- KCT0001997
- Lead Sponsor
- Han Kook Shin Yak Pharmaceutical
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 90
Inclusion Criteria
1. Subjects who have Brief Cognitive Status Exam score in K-WMS-IV(Korean-Wechsler Memory-Scale-IV) over boundary line and have Auditory Memory score or Visual Memory score below 85.(20>=age>45)
2. Subjects who have decreased SVLT(Seoul Verbal Learning Test) or RCFT(Rey Complex Figure Test) score(-1.0SD<= SVLT or RCFT score) in SNSB-II(Seoul Neuropaychological Screening Battery-II) comparing to the same age and education group.(45>=age>=65)
Exclusion Criteria
Subject with mental disorders such as schizophrenia, depressive disorder, drug intoxication
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ADAS-cog(Alzheimer’s Disease Assessment Scale-Korean version-cognitive subscale) Total score ;ADAS-cog(Alzheimer’s Disease Assessment Scale-Korean version-cognitive subscale) memory
- Secondary Outcome Measures
Name Time Method Adverse Event