Get A Grip: Spinal stimulation for upper limb and respiratory function in incomplete tetraplegia: a Bayesian Optimal Phase II trial

euroscience Research Australia (NeuRA)0 个研究点目标入组 48 人开始时间: 2023年7月24日最近更新: 2024年8月26日

适应症

试验速览

暂无简介。

•Aged 18 years or older
•- Have a motor incomplete (American Spinal Injury Association (ASIA) Impairment Scale (AIS) C or D) spinal cord injury sustained a minimum of 12 months prior to consent.
•- Able to breathe independently
•- Have an injury level between C2 and C8 neurological levels.
•- Willing and able to participate in a training program three times a week for 6 weeks

•Have a history of clinically significant autonomic dysreflexia in response to electrical stimulation
•Unable to elicit reflexes whilst experiencing the stimulation
•Cannot tolerate spinal stimulation at a therapeutic intensity
•Have a progressive neurological disease or other major neurological condition other than the spinal cord injury (e.g., severe traumatic brain injury or stroke)
•Open surgery within the last 3 months
•Syrinx (fluid-filled cyst or cavity in spinal cord) on recent MRI
•Severe upper limb spasticity or contractures
•Any serious medical condition, cognitive impairment (i.e. trouble remembering or learning), drug dependency, psychiatric illness or behavioural problem preventing you from adhering to the protocol
•Cardiac pacemaker or pregnant
•Stem cell or olfactory ensheathing cell therapy within the last 5 years
•Currently taking part, or in the follow-up period, of any other clinical trial

发起方

euroscience Research Australia (NeuRA)