Comparison of Oral Misoprostol Tablets and Oxytocin for the Induction of Labor inPremature Rupture of Membranes

Phase 3

Recruiting

Conditions: abor in premature rupture of fetal protective membranes.
Encounter for routine child health examination
Z00.12

Registration Number: IRCT20191014045106N1

Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: Female

Target Recruitment: 160

Inclusion Criteria

Definitive diagnosis of rupture of the sachet on examination with speculum or positive frenne test
Gestational age between 34 and 42 weeks
Cephalic presentation
Bishop score =5
Indication of vaginal termination of pregnancy
Parity less than five
Absence of active labor
Absence of active labor

Exclusion Criteria

The presence of any fetal heart rate abnormalities
A history of cesarean section or uterine scarring
Contraindications for vaginal delivery such as placenta peria
Known allergy to prostaglandin (skin manifestations, hives, rash, shortness of breath, cough, chest pain and blurred vision after previous prostaglandin use)
Estimated baby weight over 4 kg
Active labor means at least 3 contractions with sufficient force and duration of at least 40 seconds within 10 minutes.
Active cardiovascular disease, asthma, glaucoma
Vaginal bleeding

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Age. Timepoint: Baseline. Method of measurement: questionnaire.;Pregnancy age. Timepoint: Baseline. Method of measurement: questionnaire.;Delivery time. Timepoint: During delivery. Method of measurement: questionnaire.;First and fifth minute apgar. Timepoint: First and fifth minute. Method of measurement: Based on Apgar score determination by examiner.;Postpartum hemorrhage. Timepoint: Immediately after delivery. Method of measurement: View by examiner / Yes, No.;Excretion of neonatal meconium. Timepoint: After birth. Method of measurement: View by examiner / Yes, No.

Secondary Outcome Measures