NCT03423420CompletedNot Applicable
High Central Venous Pressure After Cardiac Surgery is Associated With Increased Morbidity and Mortality
Charite University, Berlin, Germany1 site in 1 country5,945 target enrollmentStarted: January 1, 2006Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 5,945
- Locations
- 1
- Primary Endpoint
- mortality
Study Overview
Brief Summary
Recent studies indicated the central venous pressure (CVP) as a prognostic marker. Therefore, we retrospectively analyzed the CVP on admission to the intensive care unit (ICU) in cardiac surgery patients regarding its prognostic value for morbidity and mortality.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Retrospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •In-patients of the Charité Universitätsmedizin Berlin
- •at least 18 years old
- •female or male sex
- •cardiosurgical intervention (OPS 5.35 and 5.36) between 01/06 and 12/
- •post-operative monitoring of anesthesiological intensive care unit
Exclusion Criteria
- •previous cardiosurgical interventions during the same hospital stay.
- •incomplete documentation
Outcomes
Primary Outcomes
mortality
Time Frame: an average of 30 days
In-Hospital mortality
Secondary Outcomes
- mortality rate-1(90 days)
- mortality rate-5(5 years)
- mortality rate-2(180 days)
- Central venous pressure(intensive care unit stay, an average of 5 days)
- ICU stay(an average of 5 days)
- Renal insufficiency - 3(intensive care unit stay, an average of 5 days)
- Stroke(hospital length of stay, an average of 13 days)
- Hospital stay(an average of 13 days)
- ICU readmission(an average of 30 days)
- Renal insufficiency - 1(intensive care unit stay, an average of 5 days)
- Renal insufficiency - 2(intensive care unit stay, an average of 5 days)
- mortality rate-4(1 year)
- mortality rate-3(3 years)
Investigators
Felix Balzer
Prof. Dr. med. Dr. rer. nat., MSc
Charite University, Berlin, Germany
Study Sites (1)
Loading locations...
Similar Trials
Completed
Not Applicable
Central Venous Pressure Monitoring and Prognosis of High-risk Operating PatientsCentral Venous PressureNCT04596332Fujian Provincial Hospital196
Unknown
Not Applicable
Estimation of Central Venous Pressure by Echocardiography in Intubated Children in Pediatric Intensive CareEchocardiography in Intubated Children in Pediatric Intensive CareIntubation ComplicationNCT05195424Assistance Publique - Hôpitaux de Paris120
Completed
Phase 3
Central Venous Pressure Change With Volume Challenge in Patients With Hemodynamic InstabilityAcute Circulatory FailureNCT01630577University of Monastir70
Completed
Not Applicable
Predictive effect of central venous pressure changes from passive leg elevation in homodynamic stability during anesthesia induction in adult cardiac surgeryDrug induced hypotension in anesthesia induction.Hypotension due to drugsIRCT201410111127N4Vice Chancellor for Research of Tabriz University of Medical Sciences120
Completed
Not Applicable
Comparison between central venous pressure (CVP) and stroke volume variation (SVV) as an indicator for management of fluid transfusion in patients undergoing hepatectomyliver diseasesJPRN-UMIN000011377Department of Anesthesiology, Kurume University School of Medicine30
