NCT03423420CompletedNot Applicable
High Central Venous Pressure After Cardiac Surgery is Associated With Increased Morbidity and Mortality
Charite University, Berlin, Germany1 site in 1 country5,945 target enrollmentStarted: January 1, 2006Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 5,945
- Locations
- 1
- Primary Endpoint
- mortality
Study Overview
Brief Summary
Recent studies indicated the central venous pressure (CVP) as a prognostic marker. Therefore, we retrospectively analyzed the CVP on admission to the intensive care unit (ICU) in cardiac surgery patients regarding its prognostic value for morbidity and mortality.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Retrospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •In-patients of the Charité Universitätsmedizin Berlin
- •at least 18 years old
- •female or male sex
- •cardiosurgical intervention (OPS 5.35 and 5.36) between 01/06 and 12/
- •post-operative monitoring of anesthesiological intensive care unit
Exclusion Criteria
- •previous cardiosurgical interventions during the same hospital stay.
- •incomplete documentation
Outcomes
Primary Outcomes
mortality
Time Frame: an average of 30 days
In-Hospital mortality
Secondary Outcomes
- mortality rate-1(90 days)
- mortality rate-5(5 years)
- mortality rate-2(180 days)
- Central venous pressure(intensive care unit stay, an average of 5 days)
- ICU stay(an average of 5 days)
- Renal insufficiency - 3(intensive care unit stay, an average of 5 days)
- Stroke(hospital length of stay, an average of 13 days)
- Hospital stay(an average of 13 days)
- ICU readmission(an average of 30 days)
- Renal insufficiency - 1(intensive care unit stay, an average of 5 days)
- Renal insufficiency - 2(intensive care unit stay, an average of 5 days)
- mortality rate-4(1 year)
- mortality rate-3(3 years)
Investigators
Felix Balzer
Prof. Dr. med. Dr. rer. nat., MSc
Charite University, Berlin, Germany
Study Sites (1)
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