Cardiovascular Health Improvement Project

Recruiting

Conditions: Cardiovascular Diseases
Bicuspid Aortic Valve (BAV)
Aortic Dissection
Aortic Aneurysm
Heart Failure

Brief Summary: The goal of this project is to establish a biobank of clinical information, DNA, plasma, and aortic tissue samples from patients with cardiovascular disease as well as healthy controls.

Detailed Description: The goal of this project is to establish a biobank of clinical information, DNA, plasma, and aortic tissue samples from patients with cardiovascular disease as well as healthy controls. The aims of the study are to collect biological specimens (blood, plasma, serum, aortic tissue) and family history; establish a biobank, establish a comprehensive database with information from consented patients, and provide researchers with high quality well annotated DNA samples with demographic and clinical information.

Recruitment & Eligibility

Inclusion Criteria

Any patient over the age of 18 who is able/willing to give informed consent
Patients <18 years of age with parental consent and assent (if assent is applicable for their age)
Diagnosis of:
aortic pathology potentially due to a known or suspected inherited condition
Idiopathic aortic aneurysm
Interesting of novel vascular pathology in the aorta or main branches
Family history of aortic or vascular disease
Other cardiovascular disease
Healthy controls with no apparent cardiovascular disease

Exclusion Criteria

Primary Outcome Measures

Name	Time	Method
Establishing a biobank of patients with Aortic Disease	40 years	Establish a biobank of blood, serum, plasma, tissue, and clinical data of patients with any form of aortic disease

Secondary Outcome Measures

Name	Time	Method

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