Cardiovascular Health Improvement Project
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Aortic Aneurysm
- Sponsor
- University of Michigan
- Enrollment
- 9999
- Locations
- 1
- Primary Endpoint
- Establishing a biobank of patients with Aortic Disease
- Status
- Recruiting
- Last Updated
- 11 months ago
Overview
Brief Summary
The goal of this project is to establish a biobank of clinical information, DNA, plasma, and aortic tissue samples from patients with cardiovascular disease as well as healthy controls.
Detailed Description
The goal of this project is to establish a biobank of clinical information, DNA, plasma, and aortic tissue samples from patients with cardiovascular disease as well as healthy controls. The aims of the study are to collect biological specimens (blood, plasma, serum, aortic tissue) and family history; establish a biobank, establish a comprehensive database with information from consented patients, and provide researchers with high quality well annotated DNA samples with demographic and clinical information.
Investigators
Marion Hofmann Bowman
Associate Professor of Internal Medicine
University of Michigan
Eligibility Criteria
Inclusion Criteria
- •Any patient over the age of 18 who is able/willing to give informed consent
- •Patients \<18 years of age with parental consent and assent (if assent is applicable for their age)
- •Diagnosis of:
- •aortic pathology potentially due to a known or suspected inherited condition
- •Idiopathic aortic aneurysm
- •Interesting of novel vascular pathology in the aorta or main branches
- •Family history of aortic or vascular disease
- •Other cardiovascular disease
- •Healthy controls with no apparent cardiovascular disease
Exclusion Criteria
- •Not willing or able to sign the consent
Outcomes
Primary Outcomes
Establishing a biobank of patients with Aortic Disease
Time Frame: 40 years
Establish a biobank of blood, serum, plasma, tissue, and clinical data of patients with any form of aortic disease