A Comparative Study of Low Intensity Pulsed Ultrasound (Osteotron IV) Versus High Intensity Continuous Ultrasound Therapy in Knee Osteoarthritis
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Osteoarthritis
- Sponsor
- Ministry of Health and Sports, Myanmar
- Enrollment
- 86
- Locations
- 1
- Primary Endpoint
- Percentage of participants with tingling
- Last Updated
- 5 years ago
Overview
Brief Summary
To compare the effects of low intensity pulsed ultrasound with high intensity continuous ultrasound in knee osteoarthritis
Detailed Description
Knee osteoarthritis is a common disorder affecting elderly and obese. Currently, there are 3 types of treatment; pharmacological, non-pharmacological and surgery. Though ultrasound, a non-pharmacological treatment, is increasingly used in knee osteoarthritis, the advantages and disadvantages of low intensity pulsed ultrasound (LIPUS) and high intensity continuous ultrasound (HICUS) are yet to be clarified. Therefore, a randomized control trial will be done to compare LIPUS and HICUS in participants with knee osteoarthritis presenting to Department of Physical Medicine and Rehabilitation, Yangon General Hospital, Myanmar.
Investigators
Wunn Lei Thwe
Principal Investigator
Ministry of Health and Sports, Myanmar
Eligibility Criteria
Inclusion Criteria
- •Participants with knee pain (VAS 3 to 6)
- •Kellgren and Lawrence grade 2 and 3 in X' ray knee joint
Exclusion Criteria
- •Rheumatoid arthritis, Gouty arthritis, Spondyloarthropathies, Metabolic arthropathies
- •Infection of knee joint
- •Tumor of knee joint
- •History of hypersensitivity to heat
- •Previous knee surgery in affected side
- •Intra-articular injection within previous 3 months
- •Participants taking treatment with other physical modalities such as low-level laser therapy and Trans Cutaneous Electrical Nerve Stimulation
Outcomes
Primary Outcomes
Percentage of participants with tingling
Time Frame: 8 weeks
Tingling sensation, a possible complication of ultrasound therapy, will be recorded as a dichotomous variable (i.e. present or absent).
Visual Analog Scale (VAS)
Time Frame: 8 weeks
It is one of the most commonly used measures of pain intensity and it is divided into 10 ordinal ratings with 0 being "no pain" and 10 being "pain as bad as it could be".
Western Ontario McMaster University Osteoarthritis Index Inventory (WOMAC)
Time Frame: 8 weeks
This index measures clinically important symptoms of pain, stiffness and function. It consists of 23 questions (5 pain, 2 stiffness and 16 physical function) and the maximum score is 100, indicating the worst outcome while the minimum score is 0, indicating the best outcome.
Percentage of participants with skin irritation
Time Frame: 8 weeks
Skin irritation, a possible complication of ultrasound therapy, will be recorded as a dichotomous variable (i.e. present or absent).
Percentage of participants with oedema
Time Frame: 8 weeks
Oedema, a possible complication of ultrasound therapy, will be recorded as a dichotomous variable (i.e. present or absent).
Percentage of participants with burns
Time Frame: 8 weeks
Burns, a possible complication of ultrasound therapy, will be recorded as a dichotomous variable (i.e. present or absent).