The Impaction of Exercise Training on Bone Mineral Density in Patients After Total Knee Arthroplasty
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Knee Osteoarthritis
- Sponsor
- Chang Gung Memorial Hospital
- Enrollment
- 110
- Locations
- 1
- Primary Endpoint
- Change from baseline bone mineral density
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
Rehabilitation after total knee arthroplasty (TKA) should consider control of postoperative pain and swelling, protection of the healing graft, restoration of full range of motion symmetric to the contralateral knee, strengthening of the muscles that stabilize the knee, hip, and trunk, enhancing neuromuscular control, and a gradual progression to functional activities that are required for return to the normal daily life. The effects of concomitant injuries and surgical procedures must also be considered in planning an individualized rehabilitation program. However, it is still unclear regarding the optimal exercise prescription after TKA. In the current study, the investigators plan to develop an exercise protocol and evaluate the result in a multidisciplinary approach, i.e. bone mineral density assessment. The exercise prescription consisted of cyclic exercise, aerobic exercise and resistant training exercise for first, second and third year, respectively. Cyclic exercise is advantaged safety and effectiveness of hydraulic resistance equipment, as well as the exercise can be quantitatively determined. Aerobic exercise is privileged by the cardiopulmonary endurance improvement, along with muscle strengthening in the associated muscle groups. Resistance exercise is specified for the indicated muscle groups, especially knee extensors, flexors, ankle plantar flexor and dorsi flexor in TKA reconstructed patients. The investigators hypothesis that using this cyclic exercise process can improve the body composition, muscle strength, bone mass density, level of oxidative damage indicators, gait performance, quality of life, knee joint range of motion, function of cardiopulmonary and fitness. This project will establish the scientific basis for rehabilitation protocol involving knee surgery.
Investigators
Robert Wen-Wei Hsu
Honorary Dean
Chang Gung Memorial Hospital
Eligibility Criteria
Inclusion Criteria
- •The inclusion criteria of this study were the patients diagnosed with serious osteoarthritis (OA) and recommended to receive TKA surgery.
Exclusion Criteria
- •The exclusion criteria were the patients with Diabetes, Neuromusculoskeletal disorder, severe chronic disease, history of fracture of a lower limb, artificial limb, and unsuitable for exercise training
Outcomes
Primary Outcomes
Change from baseline bone mineral density
Time Frame: pre-operation; three month ; six month and nine month after operation; twelve-month follow-up
Bone mineral density measurement is measured by dual-energy x-ray absorptiometry (DXA). Measurements are made over the lumbar spine and over the upper part of the hip and the measurement is assessed at pre-operation, three month, six month and nine month after operation, and twelve-month follow-up.
Secondary Outcomes
- Change from baseline KOOS questionnaire assessment(pre-operation; three month ; six month and nine month after operation; twelve-month follow-up)
- Physical fitness---6-minutes' walk test(pre-operation; three month , six month and nine month after operation; twelve-month follow-up)
- Physical fitness---30-sec sit to stand(pre-operation; three month ; six month and nine month after operation; twelve-month follow-up)
- Physical fitness---2.44 m up and go(pre-operation; three month ; six month and nine month after operation; twelve-month follow-up)
- Motion analysis(pre-operation; three month ; six month and nine month after operation; twelve-month follow-up)
- Change from baseline lower extremity muscle strength(pre-operation; three month ; six month and nine month after operation; twelve-month follow-up)
- Change from baseline SF-36 questionnaire assessment(pre-operation; three month ; six month and nine month after operation; twelve-month follow-up)