An Open Label Clinical Non-Randomized Study to Evaluate the Efficacy of Patola-Nimbadi Basti in the Management of Psoriasis w.s.r. to Ekakushtha
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Relieve in the sign and symptoms of Psoriasis
研究概览
简要总结
Psoriasis is one of the most common dermatological diseases. It is a complex, chronic, multi-factorial, non-contagious inflammatory skin disease characterized by erythematous, sharply demarcated papules and rounded plaques, covered by silver shiny scale. Eka kushtha consists of sign and symptoms i.e. Aswedanam,Mahavastu and Matsya Shakalopam Avastha which can be compared with Psoriasis and hence it has been taken analogue to Psoriasis in present research work. In present study, Basti Chikitsa is selected because Acharya Sushrut described the indication of Basti in sansargaj and sannipataj vikara. Due to dominance of Tridosha in Kushtha and mainly Vata, Kapha in Eka Kushtha, favoured the treatment of Patola-Nimabadi Basti.The dravya of Patola-Nimbadi Basti is Tikta rasatmaka. Tikta dravya are Deepak, Pachak and Kaphaghna, Lekhan and Vishghana in nature and the effect on skin is Kandughna, Daha-Prashaman and Sthirikaran. Therefore, Patol-Nimbadi Basti is selected in management of Psoriasis
Aim: Evaluation of Patola-Nimbadi Basti in management of Psoriasis (Eka Kushtha).
Objective: To Evaluate Efficacy of Patola-Nimbadi Basti in management of Psoriasis (Eka Kushtha).
Research Hypothesis (H1):- Patola-Nimbadi Basti is effective in the management of Psoriasis (Eka Kushtha).
Null Hypothesis (H0):- Patola-Nimbadi Bastiis not effective in the management of Psoriasis (Eka Kushtha).
Study Plan: 30 patients will be selected of psoriasis on the basis of selection criteria. All patients will be given Patola-nimbadi Niruh basti and Goghrit Anuvasan basti as per the schedule of kala basti for 15 daya. Observations will be done on the basis of before and after subjective and objective parameters.
Analysis will be done after 15 days of Basti treatment and at 30th and 45th day as follow up.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 20.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Subjects presenting with clinical features of Psoriasis.
- •Patients suffering from psoriasis with less than 50% of the body surface involvement.
- •Subjects with chronicity of disease more than 6 months and less than 5 yrs.
- •The patient who is fit for Basti Karma (Basti Yogya).
排除标准
- •Patient presenting with clinical features other than psoriasis like generalized skin lesions, herpes simplex, herpes zooster, scabies, acne, urticaria and immunological medicated skin diseases like pemphigus vulgaris, dermatitis herpetiformis, guttate psoriasis, pustular psoriasis, lupus erythematous, psoriatic arthropathy etc.
- •Patient suffering from severe psoriasis with more than 50% of the body surface involvement.
- •Patient with chronicity of disease less than 6 months and above 5 yrs.
- •Subjects of either sex age below 20 years and above 60 years.
- •Patient on medication like corticosteroids, phototherapy, biologics, antidepressant and any other drugs that may have an influence on the outcome of the study .
- •Alcoholics or drug abusers.
- •Systemic Lupus Erythematous and other Auto Immune disorders.
- •Patients having systematic pathologies like cardiac diseases, renal diseases and endocrine disorders.
- •Pregnant and lactating women.
结局指标
主要结局
Relieve in the sign and symptoms of Psoriasis
时间窗: 45th day after treatment.
次要结局
- 1. To improve quality of life of patient.(2. Remove the stress factor of Psoriasis patient.)
研究者
Dr Himanshu
Institute for Ayurved Studies and Research Umri Road Sector 08 Kurukshetra Haryana 136118