Fertility and desire to have children in young adults with cancer

• Conditions: CancerReproductive Concerns

• Registration Number: DRKS00028832
• Lead Sponsor: Institut und Poliklinik für Medizinische Psychologie

Brief Summary

Results: High satisfaction with education was associated with less reproductive concerns. Furthermore, education and implementation of fertility-preserving interventions were associated with lower decision regret (R2 = .25). Female AYAs, those with shorter time since diagnosis and AYAs with higher mental strain reported more reproductive concerns. After guideline introduction, women were more frequently counselled, whereas for men the opposite was true. A four- rather than six-factorial model was proposed for the German version of the RCAC scale. Conclusions: The results indicate that education and implementation of fertility-preserving measures in Germany require improvement. Especially, high-quality fertility-related education is needed. Moreover, prevention should address fertility-related concerns early in vulnerable groups.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-06-27
• Study Completion: 2022-09-03
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

History of cancer between 15 and 39 years of age

Exclusion Criteria

Age under 18 years or over 50 years

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reproductive Concerns (RCAC-Scale)

Secondary Outcome Measures

Name	Time	Method
Mental well-being (NCNN distress thermometer; PHQ-4; VAS of EQ-5-D; EORTC QLQ-C30)