Iron Status and Lung Function in Pediatric Asthma

Completed

• Conditions: Pulmonary Function Tests

• Registration Number: NCT05277610
• Lead Sponsor: Ain Shams University

Brief Summary

Iron has a variable role regarding asthma and respiratory function. In addition, iron deficiency may affect spirometry results in asthmatic children. So, we aimed to assess the effect of ion status on lung function in childhood asthma

Detailed Description

This cross-sectional study included fifty asthmatic children in the age group of 6-16 years. Asthmatic patients were classified according to their complete blood count and iron profile into 2 groups: group 1; asthmatic children without iron deficiency anemia (IDA), group 2; asthmatic children with IDA. All patients underwent full history taking, clinical examination, laboratory investigations, asthma control test, and pulmonary function tests.

Pulmonary function testing was performed using standardized spirometry. Lung function was measured by forced expiratory volume in one second (FEV1), forced vital capacity (FVC), FEV1/FVC, and maximal mid-expiratory flow (MMEF 25-75%) of FVC. both patients' groups are compared.

Study Timeline

• Study Start: 2019-06-01
• Primary Completion: 2019-08-01
• Study Completion: 2019-10-01
• Status Verified: 2022-03
• Study First Submitted: 2022-03-04
• Study First Submitted QC: 2022-03-04
• Last Update Submitted: 2022-03-04
• Study First Posted: 2022-03-14
• Last Update Posted: 2022-03-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Confirmed diagnosis of bronchial asthma: The diagnosis of bronchial asthma in the studied children was based on clinical examination The diagnosis of iron deficiency anemia was supported by criteria provided and updated by the World Health Organization

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Exclusion Criteria

• chronic lung diseases other than asthma Severe systemic illnesses such as liver, renal diseases, and nutritional disorders

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
improved asthma control	2 months	higher asthma control test

Trial Locations

Locations (1)

Heba Omara; 🇪🇬 Cairo, Lecturer/Instructor, Egypt