Oral Manifestations in Chronic Kidney Disease.

Completed

• Conditions: Chronic Kidney Diseases; Peritoneal Dyalisis; Hemodyalysis; Pre-dyalisis

• Registration Number: NCT06487689
• Lead Sponsor: José López Lopez

Brief Summary

The goal of this observational study is to investigate oral manifestations in patients with Chronic Kidney Disease (CKD) for early detection, that alterations play an important point for dental guide during the progression and type of treatment of CKD .

An oral exam was performed for detection oral manifestations, age, smoking, alcoholic and oral hygiene habits were collected.

The study has 3 groups under study: hemodialysis (HD), peritoneal dialysis (PD) and pre-dialysis (P-D)

Detailed Description

Not available

Study Timeline

• Study Start: 2024-01-10
• Primary Completion: 2024-03-15
• Study Completion: 2024-05-25
• Status Verified: 2024-06
• Study First Submitted: 2024-06-12
• Study First Submitted QC: 2024-06-27
• Last Update Submitted: 2024-06-27
• Study First Posted: 2024-07-05
• Last Update Posted: 2024-07-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 449

Inclusion Criteria

• Age ≥ 18 years and ≤ 80 years;
• No change of medication in the last 3 months;
• History of CKD comported by data laboratory (GRF<60 ml/min/1.73m²).

Exclusion Criteria

• Age ≤ 18 years and ≥ 80 years;
• Patients undergoing orthodontic therapy;
• Patients taking drugs;
• Patients changes the medication or introduced a new medication.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Periodontal status	2 years	periodontrogram (probe CP12)

Secondary Outcome Measures

Name	Time	Method
oral lesions	2 years	qualitative variable: uremic odor, xerostomia, taste disorder, petechiae, tongue coating
smoking and alcohol habits	2 years	qualitative variable: YES/NO
Sex	2 years	qualitative variable: Male/Female
time of treatment	2 years	nominal variable: years
Age	2 years	nominal variable: years
Type of CKD	2 years	qualitative variable: pre-dialysis, peritoneal dialysis, hemodialysis
time with CKD	2 years	nominal variable: years

Trial Locations

Locations (1)

University of Barcelona; 🇪🇸 Hospitalet de Llobregat, Barcelona, Spain