Prevalence Of Microalbuminuria Among Children Suffering From Sickle Cell Nephropathy and Sickle Cell/Beta-Thalassemia

• Conditions: Sickle Cell Anemia; Beta-Thalassemia; Microalbuminuria
• Interventions: Other: No intervention

• Registration Number: NCT01092169
• Lead Sponsor: Hillel Yaffe Medical Center

Brief Summary

Sickle cell nephropathy is a known complication of sickle cell anemia (SCA) manifested by increase in glomerular filtration rate (glomerular hyperfiltration) and results in proteinuria and chronic renal failure.

Our goal is to examine the prevalence of proteinuria and microalbuminuria as an early predictive factor of glomerular injury, among young people who suffer from SCA as well as those who suffer from combined sickle cell/beta-thalassemia.

Detailed Description

Not available

Study Timeline

• Status Verified: 2010-03
• Study First Submitted: 2010-03-23
• Study First Submitted QC: 2010-03-23
• Last Update Submitted: 2010-03-23
• Study First Posted: 2010-03-24
• Last Update Posted: 2010-03-24

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• Patients diagnosed with sickle cell anemia
• Patients diagnosed with combined sickle cell anemia/beta-thalassemia

Exclusion Criteria

• Diabetes mellitus
• Hypertension
• Reduced renal mass (single kidney)
• Overweight
• History of UTIs

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Sickle cell beta	No intervention	-