Study on the correlation between fire-needle pain and analgesic effect in treating acute herpes zoster
- Conditions
- Acute herps zoster
- Registration Number
- ITMCTR2100004853
- Lead Sponsor
- South District of Guang'anmen Hospital, China Academy of Chinese Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
1. Meet the diagnostic criteria for herpes zoster;
2. Aged range from 18 to 75 years;
3. No antiviral drugs or analgesics have been taken or used externally within 1 week;
4. Neuropathic pain vas value >= 50%;
5. Sign the informed consent form and volunteer to participate in this research.
1. Special types, such as meningeal herpes zoster, visceral herpes zoster, eye and ear herpes zoster, generalized herpes zoster, non-rash type herpes zoster, etc.;
2. Patients who are highly allergic to amide local anesthetics or to any other ingredients in compound lidocaine cream;
3. Long-term use of corticosteroids or immunosuppressive agents;
4. Patients with congenital or idiopathic methemoglobinemia;
5. Women who are breastfeeding, pregnant or preparing to become pregnant;
6. Patients with severe primary diseases or systemic failure such as cardiovascular, cerebrovascular, liver, kidney, hematopoietic system, patients with atopic dermatitis, psychiatric patients, hemophilia patients, and patients with bleeding tendency;
7. Patients who are in a critical condition and are difficult to make an accurate assessment of the effectiveness and safety of the treatment;
8. Patients with scar constitution.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The change of the VAS score from baseline in the most painful degree of acute neuralgia in local herpes zoster;
- Secondary Outcome Measures
Name Time Method The time required for constant pain intensity of VAS below 30%;Percentage of patients with the most painful VAS score of herpes zoster acute neuralgia decreased to less than 30%;