NCT03617289CompletedNot Applicable
Efficacy of Magnesium Sulfate on Reducing Renal Colic in the Emergency Department
Conditions
Interventions
Drugs
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Henry Ford Health System
- Enrollment
- 37
- Primary Endpoint
- Pain Score Change
Study Overview
Brief Summary
To determine if magnesium sulfate paired with an analgesic medication will improve patient pain from renal colic compared with analgesic alone.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Single (Participant)
Eligibility Criteria
- Ages
- 18 Years to 100 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Age >18 years old and <100 years old.
- •Patients seen in the Emergency Department at Henry Ford Macomb hospital.
- •Patients that are A+Ox
- •Patients who have typical presentation for renal colic.
Exclusion Criteria
- •Age <18 years.
- •Patients with a history of dementia, acute delirium or altered mental status.
- •Patients with inability to consent to study or inability to fill questionnaire independently.
- •Patients with chronic kidney disease and allergies to study drugs.
- •Patients that are pregnant (women who are of child-bearing potential will be screened with a urine BHCG).
- •Patients with stroke activation or symptoms.
- •Patients with trauma activations.
- •Patients over the age of 100 years old are excluded as they make up a small percentage of the population and may become identifiable because of their age.
- •Imaging study does not show evidence of ureteral stone.
Arms & Interventions
Treatment
Experimental
Receiving Magnesium Sulfate
Intervention: Magnesium Sulfate (Drug)
Placebo
Placebo Comparator
Receiving Dextrose 5% in Water (D5W)
Intervention: D5W (Drug)
Outcomes
Primary Outcomes
Pain Score Change
Time Frame: 1 hour after the completion of treatment medication (Placebo or Study Drug)
We asked the patient's pain score on a scale of 0-10 with 10 being the highest amount of pain and 0 no pain, before and after treatment (approximately 1 hour). Primary Outcome was the change in score before and after treatment.
Secondary Outcomes
- Percentage of Participants Requiring Opiates for Additional Pain Control(Any opiate administration required after re-evaluation of pain score after initial treatment with either placebo or study drug)
Investigators
Jason Muir
Principal Investigator
Henry Ford Health System
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