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Clinical Trials/NCT03617289
NCT03617289CompletedNot Applicable

Efficacy of Magnesium Sulfate on Reducing Renal Colic in the Emergency Department

Henry Ford Health System0 sites37 target enrollmentStarted: January 2016Last updated:
Conditions
Interventions
Drugs

Trial Snapshot

Phase
Not Applicable
Status
Completed
Enrollment
37
Primary Endpoint
Pain Score Change

Study Overview

Brief Summary

To determine if magnesium sulfate paired with an analgesic medication will improve patient pain from renal colic compared with analgesic alone.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Treatment
Masking
Single (Participant)

Eligibility Criteria

Ages
18 Years to 100 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Age >18 years old and <100 years old.
  • Patients seen in the Emergency Department at Henry Ford Macomb hospital.
  • Patients that are A+Ox
  • Patients who have typical presentation for renal colic.

Exclusion Criteria

  • Age <18 years.
  • Patients with a history of dementia, acute delirium or altered mental status.
  • Patients with inability to consent to study or inability to fill questionnaire independently.
  • Patients with chronic kidney disease and allergies to study drugs.
  • Patients that are pregnant (women who are of child-bearing potential will be screened with a urine BHCG).
  • Patients with stroke activation or symptoms.
  • Patients with trauma activations.
  • Patients over the age of 100 years old are excluded as they make up a small percentage of the population and may become identifiable because of their age.
  • Imaging study does not show evidence of ureteral stone.

Arms & Interventions

Treatment

Experimental

Receiving Magnesium Sulfate

Intervention: Magnesium Sulfate (Drug)

Placebo

Placebo Comparator

Receiving Dextrose 5% in Water (D5W)

Intervention: D5W (Drug)

Outcomes

Primary Outcomes

Pain Score Change

Time Frame: 1 hour after the completion of treatment medication (Placebo or Study Drug)

We asked the patient's pain score on a scale of 0-10 with 10 being the highest amount of pain and 0 no pain, before and after treatment (approximately 1 hour). Primary Outcome was the change in score before and after treatment.

Secondary Outcomes

  • Percentage of Participants Requiring Opiates for Additional Pain Control(Any opiate administration required after re-evaluation of pain score after initial treatment with either placebo or study drug)

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Jason Muir

Principal Investigator

Henry Ford Health System

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