A comparative add on clinical trial to evaluate the effectiveness of Vranaropana taila against Jatyadi taila as external application in Dushtavrana with special reference to Neurogenic ulcers.
试验速览
- 阶段
- Phase 3 4
- 状态
- 已完成
- 发起方
- 入组人数
- 24
- 试验地点
- 1
- 主要终点
- 1 Number of ulcers
研究概览
简要总结
A comparative add on superiority trial is planned in non healing ulcers with special reference to neurological ulcers to compare the topical application of vranaropana taila against jatyadi taila. Conventionally antibiotics are used for treating chronic ulcers, but antibiotic resistance is a biggest challenge now a days. At the same time plant derived antibiotics acts predominantly by breaking the cell wall and cell membrane of microbes which ultimately leads to their death.Even though some formulations are being used for treating chronic ulcers, there are some medicines that are yet to be explored. Here an attempt is made to explore Vranaropana taila as topical application in chronic ulcer. The outcome measurements will be done by using some assessment criteria like granulation tissue, epithelialisation, drainage amount etc.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- None
入排标准
- 年龄范围
- 21.00 Year(s) 至 70.00 Year(s)(—)
- 性别
- All
入选标准
- •1 Subjects satisfying diagnostic criteria of Neurogenic ulcers 2Subjects within the age limit of 21-70 years irrespective of gender 3 Participants with informed consent.
排除标准
- •1 Uncontrolled Diabetes mellitus HbA1c more than 7.5 2 Ulcer size more than 10 cm 3 Known cases of TB, HIV, Malignancy, Lepromatous ulcer, Burns.
结局指标
主要结局
1 Number of ulcers
时间窗: 0th, 7th, 14th, 21st,28th day
2 Size of ulcers
时间窗: 0th, 7th, 14th, 21st,28th day
3 Granulation tissue formation
时间窗: 0th, 7th, 14th, 21st,28th day
4 Epithelialisation
时间窗: 0th, 7th, 14th, 21st,28th day
6 Drainage amount
时间窗: 0th, 7th, 14th, 21st,28th day
次要结局
未报告次要终点
研究者
Dr Sajiya K T
VPSV Ayurveda College, Kottakkal
