JPRN-UMIN000015414
Completed
未知
Exploratory clinical study of first-line treatment for patients with advanced EGFR mutation-positive non-squamous non-small-cell lung cancer - Exploratory clinical study of first-line treatment for patients with advanced EGFR mutation-positive non-squamous non-small-cell lung cancer
Department of Thoracic Oncology Osaka Medical Center for Cardiovascular diseases0 sites40 target enrollmentOctober 11, 2014
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- advanced EGFR mutation-positive non-squamous non-small cell lung cancer
- Sponsor
- Department of Thoracic Oncology Osaka Medical Center for Cardiovascular diseases
- Enrollment
- 40
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •1\.EGFR mutation Exon20 T790M positive 2\.Symptomatic brain metastasis and a spinal metastases requiring surgical treatment or irradiation 3\.Less than 5 years of disease\-free interval with other malignancy 4\.Pleural effusion, ascites or pericardial fluid in need of treatment 5\.SVC syndrome 6\.Spinal cord compression with symptoms 7\.Cerebrovascular disorder with aymptoms 8\.Unhealed fracture 9\.Severe infection 10\.Planned surgery during the study period 11\.Obvious interstitial lung disease 12\.Severe gastrointestinal disorder 13\.Symptomatic corneal disease 14\.Severe cardiac disease 15\.Clinically significant drug allergy 16\.Prior EGFR\-TKI therapy 17\.During pregnabcy or lactating woman 18\.Uncontrolled psychiatric disease 19\.Other
Outcomes
Primary Outcomes
Not specified
Similar Trials
Active, not recruiting
Phase 1
Clinical trial to investigate the efficacy of treatment combination with gemcitabine and pazopanib in patients with inoperable locally advanced or metastatic gallbladder and bile duct cancerInoperable locally advanced or metastatic cancer of the biliary tree (cholangiocarcinoma and gallbladder carcinoma)MedDRA version: 14.1Level: LLTClassification code 10017620Term: Gallbladder carcinomaSystem Organ Class: 100000004864MedDRA version: 14.1Level: LLTClassification code 10008593Term: CholangiocarcinomaSystem Organ Class: 100000004864MedDRA version: 14.1Level: LLTClassification code 10004655Term: Biliary carcinomaSystem Organ Class: 100000004864Therapeutic area: Diseases [C] - Cancer [C04]EUCTR2012-001705-24-GRHellenic Cooperative Oncology Group46
Completed
Not Applicable
To study early treatment response in peripheral blood on Day 15 in B cell Acute Lymphoblastic Leukemia patientsHealth Condition 1: null- B cell Acute Lymphoblastic LeukemiaCTRI/2016/08/007180Tata Memorial Hospital100
Not yet recruiting
Phase 1
Clinical study for the first-line treatment of advanced hepatocellular carcinoma with anrotinib hydrochloride capsuleITMCTR1900002329Guilin Traditional Chinese Medicine Hospital
Completed
Not Applicable
The clinical study for evaluating the early efficacy and safty of alpha-1-adrenoreceptor antagonists in patient with benign prostatic hyperplasia.Benign prostatic hyperplasia (BPH)JPRN-UMIN000005151Department of Renal and Urologic Surgery, Asahikawa Medical University100
Active, not recruiting
Phase 1
Study of safety and efficacy of genome-edited hematopoietic stem and progenitor cells in sickle cell disease (SCD)EUCTR2019-003489-41-ITOVARTIS PHARMA AG30