Monitoring exposure of Western Victorian farmers to organophosphate pesticides

Not Applicable

Recruiting

• Conditions: Organophosphate exposure; Insulin resistance (Fasting blood sugar); Public Health - Health service research; Injuries and Accidents - Poisoning

• Registration Number: ACTRN12616001130459
• Lead Sponsor: Deakin University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-08-19
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Farmers and farm workers, who are routinely working with agrichemicals , particularly those containing organophosphate (AChE inhibiting chemicals), Have not had a previous chemical known incident, are not suffering from a known chronic disorder, not taking anti-inflammatory drugs or supplements. Participants will need to report usage/exposure to OP throughout the course of the study. Competent to decide and have capacity to consent to participate in the study and, attend a health assessment. Live in south west Victoria.

Exclusion Criteria

Participants of under 18 years of age and who have a recent known chemical incident, or are suffering from a known chronic disease or are taking anti-inflammatory drugs or supplements

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Difference in average cholinesterase activity using a capillary blood sample[Assessed at baseline, then monthly for a period of 12 months];Link between cholinesterase activity (assessed using a capillary blood sample) and organophosphate use (self reported)[Cholinesterase activity will be assessed at baseline, then monthly for a period of 12 months; data on organophosphate use within the last month at each assessment will be collected]

Secondary Outcome Measures

Name	Time	Method
Stress level assessed using Kessler K10 questionnaire[Baseline];Mean fasting blood glucose assessed by capillary blood sample[Baseline];Mean fasting cholesterol levels assessed by capillary blood sample[Baseline]