Nutrition Childhood Cancer Survivors

• Conditions: Childhood Cancer; Nutrition Disorders

• Registration Number: NCT05481229
• Lead Sponsor: Masaryk University

Brief Summary

NUTRITION CCS is a cross-sectional, descriptive study to assess the relationship between body composition and demographic, socioeconomic status, treatment modalities and blood samples of survivors who were in remission. The study was conducted in the Clinic for childhood cancer survivors. The clinic is attended by patients older than 18 years and was built in 2016 at the St. Anne's Hospital in Brno.

Detailed Description

NUTRITION CCS is a cross-sectional, descriptive study to assess the relationship between body composition and demographic, socioeconomic status, treatment modalities and blood samples of survivors who were in remission.

Objectives of the study

1. to determine the prevalence (incidence) of nutritional disorders, especially obesity and metabolic syndrome, in cured paediatric cancer patients in adulthood;

2. to investigate the role of adipokines in the development of cardiometabolic complications in this group of patients; 3. to determine whether targeted dietary and lifestyle interventions can lead to improvements in nutritional status and subjectively perceived quality of life of treated paediatric cancer patients in adulthood and objectively assessed cardiometabolic risk

Study Timeline

• Study Start: 2018-04-25
• Status Verified: 2022-07
• Study First Submitted: 2022-07-25
• Study First Submitted QC: 2022-07-28
• Last Update Submitted: 2022-07-28
• Study First Posted: 2022-08-01
• Last Update Posted: 2022-08-01
• Primary Completion: 2023-04-25
• Study Completion: 2023-04-25

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Patients after treatment from childhood and adolescent cancers.
• The subject is male or female, aged 18 - 64 years

Exclusion Criteria

• Patients with acute cancer therapy
• Pregnant women

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Define the relationship between the levels of adipokines and cardiometabolic diseases.	through study completion, an average of 1 year	Define the relationship between the levels of selected adipokines and the risk of selected chronic diseases, specifically cardiometabolic diseases.

Secondary Outcome Measures

Name	Time	Method
Determine the prevalence of hight body fat and decreased skeletal muscle.	through study completion, an average of 1 year	Determine the number of patients with a high body fat percentage. In these patients, monitor the responses of selected adipokine levels to targeted nutritional intervention leading to fat mass reduction.

Trial Locations

Locations (2)

Masaryk University; 🇨🇿 Brno, Czechia

St. Anne Hospital in Brno; 🇨🇿 Brno, Czechia