EUCTR2006-006576-38-AT
Active, not recruiting
Not Applicable
ongitudinal imaging of serotonin transporter occupancy using PET and [11C]DASB in patients with major depression treated with escitalopram or citalopram - PET with DASB comparing escitalopram to citalopram
Siegfried KASPER, O.Univ.Prof.Dr.Dr.h.c., Medizinische Universität Wien0 sitesAugust 16, 2007
ConditionsMajor depression
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Major depression
- Sponsor
- Siegfried KASPER, O.Univ.Prof.Dr.Dr.h.c., Medizinische Universität Wien
- Status
- Active, not recruiting
- Last Updated
- 14 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Male or female
- •Age 18 – 55 years
- •DSM\-IV diagnosis of major depression
- •A score of 16 or greater on the 17\-item HAM\-D
- •Signed informed consent form
- •Negative urine pregnancy test in women at the screening visit and PET days.
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1\.2 Adults (18\-64 years) yes
- •F.1\.2\.1 Number of subjects for this age range
Exclusion Criteria
- •Concomitant major medical or neurological illness
- •Clinically relevant abnormalities on a general physical examination and routine laboratory screening
- •Current substance abuse
- •Use of SSRIs or other drugs with affinity to SERT within last 3 months (or use of fluoxetine within last 4 months)
- •Any exposure to artificial radiation within 6 months prior to the inclusion into the present study
Outcomes
Primary Outcomes
Not specified
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