跳至主要内容
临床试验/EUCTR2006-006576-38-AT
EUCTR2006-006576-38-AT进行中(未招募)不适用

ongitudinal imaging of serotonin transporter occupancy using PET and [11C]DASB in patients with major depression treated with escitalopram or citalopram - PET with DASB comparing escitalopram to citalopram

Siegfried KASPER, O.Univ.Prof.Dr.Dr.h.c., Medizinische Universität Wien0 个研究点开始时间: 2007年8月16日最近更新:
适应症
相关药物

试验速览

阶段
不适用
状态
进行中(未招募)
发起方

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional clinical trial of medicinal product

入排标准

性别
All

入选标准

  • Male or female
  • Age 18 – 55 years
  • DSM-IV diagnosis of major depression
  • A score of 16 or greater on the 17-item HAM-D
  • Signed informed consent form
  • Negative urine pregnancy test in women at the screening visit and PET days.
  • Are the trial subjects under 18? no
  • Number of subjects for this age range:
  • F.1.2 Adults (18-64 years) yes
  • F.1.2.1 Number of subjects for this age range
  • F.1.3 Elderly (>=65 years)
  • F.1.3.1 Number of subjects for this age range

排除标准

  • Concomitant major medical or neurological illness
  • Clinically relevant abnormalities on a general physical examination and routine laboratory screening
  • Current substance abuse
  • Use of SSRIs or other drugs with affinity to SERT within last 3 months (or use of fluoxetine within last 4 months)
  • Any exposure to artificial radiation within 6 months prior to the inclusion into the present study

研究者

发起方
Siegfried KASPER, O.Univ.Prof.Dr.Dr.h.c., Medizinische Universität Wien

相似试验