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PRESSURE CHECK: Find Your Path to Better Health

Not Applicable
Recruiting
Conditions
Blood Pressure
Interventions
Other: Remote Blood Pressure (BP) Management Program (RBPM)
Behavioral: Community Health Worker (CHW)
Registration Number
NCT06122246
Lead Sponsor
Yale University
Brief Summary

This study seeks to develop the evidence for a sustainable, community-partnered, multi-level health system strategy to improve blood pressure control. Two team-based approaches are being tested: 1) a medical model of remote BP management (RBPM) alone, and 2) RBPM plus a social model with a community health worker (CHW). These 2 strategies are being compared with a standard community screening program with referral to primary care.

Detailed Description

In this comparative effectiveness trial, we aim to answer the research question of whether a remote blood pressure management program (RBPM, inclusive of home blood pressure monitoring and telehealth visits with a nurse or pharmacist) alone or an RBPM program with community health worker (CHW) support is more effective than standard screening with education and referral to primary care in controlling blood pressure and addressing social determinants that lead to poor health outcomes.

This is a multisite study using a stepped wedge design. Health systems in 4 different cities are each partnered with 10 community based organizations (CBOs). CBOs are randomized into one of 4 sequences. Each sequence moves through the 3 study arms at different time points: Community Standard, RBPM alone, and RBPM+CHW.

At the CBOs, research health advocates screen for hypertension. Qualifying individuals who provide informed consent can enroll in the study and are assigned to the intervention that the CBO is in at that particular time. All participants receive a blood pressure cuff and a device that syncs their data with the research database. If enrolled in the RBPM arm, participants are scheduled for telehealth visits with the Pressure Check medical team to improve blood pressure control through lifestyle support and medication initiation/titration. If enrolled in the RBPM+CHW arm, participants additionally receive support from a CHW to help with medical visits and address social determinants of health. The primary outcome is blood pressure control at 6 months. Additional outcomes include implementation science to understand factors associated with adoption and outcomes, and 12 and 18 month blood pressure control.

In partnering with the community, health systems can extend their reach. CBO leaders support health messaging around hypertension and increase trust between the health system and their clients (patients). The two models, RBPM alone and RBPM+CHW, are based on the concept that disparities in hypertension control among Black, Latinx, and low-income populations exist because of inequities related to health system access and trust, individual-level socioeconomic and lifestyle factors, the physical/built environment, sociocultural factors, and discriminatory policies. Addressing these barriers may improve blood pressure control.

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
1440
Inclusion Criteria
  • Elevated BP, defined as an average resting BP of >=135/85 mmHg based on 3 consecutive blood pressure readings
Exclusion Criteria
  • People who are pregnant
  • Those that have end stage renal disease on dialysis
  • People receiving active chemotherapy

Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Arm && Interventions
GroupInterventionDescription
Remote Blood Pressure (BP) Management ProgramRemote Blood Pressure (BP) Management Program (RBPM)Participants will receive a remote BP management program (RBPM) inclusive of home BP monitoring and telehealth visits with a nurse or pharmacist.
Remote Blood Pressure (BP) Management Program + Community Health Worker (CHW)Remote Blood Pressure (BP) Management Program (RBPM)Participants will receive a remote BP management program (RBPM) inclusive of home BP monitoring and telehealth visits with a nurse or pharmacist plus a social model with a CHW.
Remote Blood Pressure (BP) Management Program + Community Health Worker (CHW)Community Health Worker (CHW)Participants will receive a remote BP management program (RBPM) inclusive of home BP monitoring and telehealth visits with a nurse or pharmacist plus a social model with a CHW.
Primary Outcome Measures
NameTimeMethod
Blood Pressure Control6 months

Participants will be assessed at 6 months for Blood Pressure (BP) control- defined as BP \<130/80 mmHg. To assess BP control, blood pressure will be measured in-person at the CBO (or another location) at Baseline, 6, 12 and 18 months with the primary endpoint of assessment as BP control at 6 months.

Secondary Outcome Measures
NameTimeMethod
Difference in BP control by study group, measured at CBO6 months, 12 months, 18 months

Proportion of participants with BP with:

Ideal \<120/80 mmHg Intermediate: \<=135/85 mmHg Poor: \>135/85mmHg

Difference in systolic BP between study groups, measured at CBO6 months, 12 months, 18 months

Mean difference in BP measured at CBO at baseline and follow-up; take average of last 2 of 3 measurements

Change in Well-being6 months, 12 months, 18 months

Well-being is assessed with the 12-item 100 Million Healthier Lives. Cantrill's Ladder: stratification into Thriving, Suffering, Struggling. Will assess mean differences of 0.5 as meaningfully different

Change in Lifestyle behaviors6 months, 12 months, 18 months

Differences in self-reported measures using a survey.Each measure is categorized as "ideal"(2 points), "intermediate"(1 point) or "poor" (0 point).

Trial Locations

Locations (4)

Sentara Health

🇺🇸

Norfolk, Virginia, United States

Houston Methodist

🇺🇸

Houston, Texas, United States

Massachusetts General Brigham Hospital

🇺🇸

Boston, Massachusetts, United States

Yale

🇺🇸

New Haven, Connecticut, United States

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