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A Study to Evaluate the Safety and Tolerability of Subcutaneous Treprostinil and Pharmacokinetics of a Novel LY900014 Formulation in Healthy Japanese Subjects (I8B-JE-ITRK)

Phase 1
Conditions
Healthy
Registration Number
JPRN-jRCT2080223225
Lead Sponsor
Eli Lilly Japan K.K.
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Sex
All
Target Recruitment
Not specified
Inclusion Criteria

Inclusion Criteria:
Overtly healthy Japanese
Body mass index (BMI) 18.5 - 25 kilograms per square meter (kg/m2)
Fasting plasma glucose >=71 milligrams per deciliter (mg/dL) (3.9 millimoles per liter [mmol/L]) and <108 mg/dL (6.0 mmol/L) (Part B only)
Have normal blood pressure, pulse rate, electrocardiogram (ECG), blood and urine laboratory test results that are acceptable for the study

Exclusion Criteria

Are currently enrolled in a clinical trial involving an investigational product or any other type of medical research judged not to be scientifically or medically compatible with this study
Have participated in a clinical trial involving an investigational product within the 30 days before study entry
Have previously completed or withdrawn from this study or any other study investigating treprostinil or LY900014, and have previously received the investigational product
Have or used to have health problems or laboratory test results or ECG readings that, in the opinion of the doctor, could make it unsafe to participate, or could interfere with understanding the results of the study

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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