: Serial sero-epidemiological surveillance study to monitor the trend of SARS-CoV-2, Dengue and Chikungunya infection transmission in the Vellore Demographic Health Surveillance System (HDSS)
Not Applicable
- Registration Number
- CTRI/2020/12/029564
- Lead Sponsor
- Dr Winsley Rose
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
all individuals currently residing and likely to stay in the area till the end of study (1 year) in the study area will be considered eligible for inclusion.
Exclusion Criteria
none
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method I.Estimate the sero-prevalence of SARS-CoV-2 infection in the general population <br/ ><br>II.Estimate the 4 monthly incidence of SARS-CoV-2 infection based on serial sero-surveys <br/ ><br>III.Estimate cumulative sero-conversion of SARS-CoV-2 infection over one year period <br/ ><br>IV.Estimate the sero-prevalence and annual sero conversion of Dengue and Chikungunya in a sub sample of the study <br/ ><br>Timepoint: serosurvey will be done once in 3 months for a period of one year
- Secondary Outcome Measures
Name Time Method I.Monitor the trend of SARS-CoV-2 transmission in the general population <br/ ><br>II.Determine the prevalence and incidence of SARS CoV2 sero-positivity among the members of the households with at least one seropositive individual (clustering of infection at household level)Determine the risk factors for SARS-CoV-2 infection <br/ ><br>III.Determine the duration of persistence of antibodies in individuals tested positive for SARS-CoV-2 infection <br/ ><br>Timepoint: serosurvey will be done once in 3 months for a period of one year