Pixel-by-Pixel analysis of Dynamic Contrast-enhanced MRI curve patterns in Juvenile Idiopathic Arthritis

• Conditions: Childhood arthritis; Juvenile Idiopathic Arthritis; 10003816; 10023213

• Registration Number: NL-OMON36487
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 100

Inclusion Criteria

Clinically suspected JIA with knee involvement.
Scheduled to undergo an open-bore MRI.
Written informed patients (when >12 years of age) and parental consent;Or;JIA patients with clinically inactive disease for at least 6 months.
A history of clinical evident arthritis in at least 1 knee.
Scheduled to undergo an open-bore MRI.
Written informed patients (when >12 years of age) and parental consent

Exclusion Criteria

Age <8 and >18 years.
A history of intra-articular corticosteroids injection within the last 6 months.
The need for anesthesia during the MRI examination.
General contraindications for MRI (such as renal insufficiency, pregnancy and claustrophobia).
Lack of written informed consent

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The accuracy of DCE-MRI in differentiating different stages of disease activity<br /><br>as compared to physical examination</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>n.v.t.</p><br>