Emotional modulation of attentional selection: A transcranial magnetic stimulation study

Completed

• Conditions: fundamenteel onderzoek bij gezonde proefpersonen; NA

• Registration Number: NL-OMON40338
• Lead Sponsor: Radboud Universiteit Nijmegen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 24

Inclusion Criteria

- aged between 18 and 35
- normal or corrected to normal vision
- not color blind
- normal hearing
- right- handedness
- non-smoking
- females taking contraceptives

Exclusion Criteria

Exclusion criteria for participation include metal in cranium, use of psychotropic drugs, including cannabis, XTC,amphetamines and cocaine, epilepsy or family history of epilepsy, history of closed-head injury, history of neurological or psychiatric disorders, medication use (i.e., benzodiazepines, antidepressants and neuroleptica), cardiac pacemaker, pregnancy and electronic hearing devices.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>A repeated measures ANOVA with TMS (sham TMS, left rTMS, right rTMS) and<br /><br>distractor (CS+, CS-) as factors will be carried out on difference RT score and<br /><br>error rates. If appropriate, planned comparisons between the conditions will be<br /><br>performed. The alpha level of significance will be set at 0.05 (two-tailed)<br /><br>throughout.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Pearson*s correlation coefficient will determine the correlation between the<br /><br>level of state anxiety as measured by the VAS and attentional capture by<br /><br>threatening distractors as indexed by the difference RT score. </p><br>