Comparison of Carotid Peak Systolic Velocity Variation With Aortic Peak Systolic Velocity Variation in Pediatric Non-Cardiac Surgery

Completed

• Conditions: Anesthesia, Endotracheal; Fluid Responsiveness; Mechanical Ventilation; Anesthesia, General
• Interventions: Other: Measurement of aortic and carotid Doppler peak systolic velocity variation

• Registration Number: NCT03155555
• Lead Sponsor: Post Graduate Institute of Medical Education and Research, Chandigarh

Brief Summary

The purpose of this study is to evaluate whether carotid Doppler peak systolic velocity can be an easy to measure possible surrogate for echocardiographic measurement of aortic peak systolic velocity variation which is an index of fluid responsiveness in mechanically ventilated children intra-operatively.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-12
• Study First Submitted: 2017-05-14
• Study First Submitted QC: 2017-05-15
• Study First Posted: 2017-05-16
• Primary Completion: 2017-12-17
• Study Completion: 2017-12-17
• Status Verified: 2019-04
• Last Update Submitted: 2019-04-12
• Last Update Posted: 2019-04-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 52

Inclusion Criteria

• Patients scheduled for mon-cardiac surgeries under general endotracheal anaesthesia in supine position with expected duration more than 1 hour

Exclusion Criteria

• Known congenital heart disease
• Any non-sinus rhythm, arrhythmias
• Patients on vasoactive medications
• Chest wall deformities, situs non solitus (eg. dextrocardia)
• Patients scheduled for open chest surgeries
• History of neck surgery/ carotid interventions

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Experimental	Measurement of aortic and carotid Doppler peak systolic velocity variation	Children aged 1-12 years undergoing major surgeries under general endotracheal anaesthesia with mechanical ventilation under neuromuscular blockade

Primary Outcome Measures

Name	Time	Method
Comparison of carotid peak systolic velocity variation with aortic peak systolic velocity variation	Measurements made within 3 minutes	Comparison of carotid peak systolic velocity variation with aortic peak systolic velocity variation by Bland-Altman analysis

Secondary Outcome Measures

Name	Time	Method
Correlation between aortic peak systolic velocity variation measured from apical and suprasternal windows	Measurements made within 3 minutes	Correlation between aortic peak systolic velocity variation measured from apical and suprasternal windows by Bland-Altman analysis

Trial Locations

Locations (1)

Postgraduate Institute of Medical Education & Research; 🇮🇳 Chandigarh, India