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Comparison of Insulin Aspart Produced by the NN2000 Process to the Current Process in Type 1 Diabetes

Phase 3
Completed
Conditions
Diabetes
Diabetes Mellitus, Type 1
Registration Number
NCT00604656
Lead Sponsor
Novo Nordisk A/S
Brief Summary

This trial is conducted in Europe. The aim of this trial is to investigate the safety and efficacy of insulin aspart produced by current process compared to that of insulin aspart produced by NN2000 process in subjects with type 2 diabetes.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
241
Inclusion Criteria
  • Subjects with type 1 diabetes
  • Duration of diabetes for at least 12 months
  • Treatment with insulin aspart for at least 3 months before trial start
  • Body Mass Index (BMI) below 35.0 kg/m2
  • HbA1c below 12.0%
Exclusion Criteria
  • Total insulin dosage more than 1.4 IU/kg/day
  • Recurrent major hypoglycaemia that may interfere with trial participation (as judged by the investigator)
  • Known hypoglycaemia unawareness as judged by the investigator
  • Known hypersensitivity or allergy

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Insulin aspart antibodiesAfter 6 months treatment
Secondary Outcome Measures
NameTimeMethod
Occurrence of adverse events
HbA1c
Incidence of hypoglycaemic episodes

Trial Locations

Locations (1)

Novo Nordisk Investigational Site

🇵🇱

Wroclaw, Poland

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