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The Expecting Study

Not Applicable
Active, not recruiting
Conditions
Obese
Pregnancy
Interventions
Other: Exercise Intervention
Registration Number
NCT02125149
Lead Sponsor
Arkansas Children's Hospital Research Institute
Brief Summary

The purpose of the study is to determine how a mother's health and physical activity may influence her child's growth and development.

Detailed Description

Not available

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
Female
Target Recruitment
284
Inclusion Criteria
  • BMI >30
  • >18 years of age
  • Singleton pregnancy
  • Less than 12 weeks gestation
  • Sedentary
  • Conceived without assisted fertility treatments
  • Cleared by physician to exercise
Exclusion Criteria
  • Women with pre-existing medical conditions as determined by the PI to affect the outcomes of interest
  • Women who are using recreational drugs, tobacco, or alcohol during pregnancy
  • Women with contraindications to exercise during pregnancy

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
InterventionExercise InterventionExercise intervention from 12 week gestation until delivery
Primary Outcome Measures
NameTimeMethod
Risk of obesity in infants and children2 years

Birth weight, body fat, and metabolism will be evaluated during the first 2 years of life.

Secondary Outcome Measures
NameTimeMethod
Maternal insulin sensitivity9 months

Fasted blood samples will be analyzed to assess glucose and insulin.

Maternal inflammation9 months

Markers of inflammation will be investigated in fasted serum samples.

Trial Locations

Locations (1)

Arkansas Children's Nutrition Center

🇺🇸

Little Rock, Arkansas, United States

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