跳至主要内容
临床试验/NCT00257400
NCT00257400已完成1 期

Interpersonal Psychotherapy for Depressed Women With Sexual Abuse Histories

University of Rochester2 个研究点 分布在 1 个国家目标入组 70 人开始时间: 2003年5月最近更新:
适应症

试验速览

阶段
1 期
状态
已完成
入组人数
70
试验地点
2
主要终点
Hamilton Rating Scale for Depression

研究概览

简要总结

This study will compare the effectiveness of individual versus interpersonal psychotherapy in treating depressed women with a history of sexual abuse.

详细描述

Depression is a common but serious mental disorder that affects millions of people each year. Depression can severely impact people's lives, causing them to often feel sad and hopeless, as well as affecting people's sleep patterns, concentration, and energy levels. Women with a history of abuse are at an increased risk for developing symptoms of depression. However, treatments such as interpersonal psychotherapy and individual psychotherapy have been known to reduce symptoms of depression. This study will compare the effectiveness of individual and interpersonal psychotherapy in improving depressive symptoms and daily functioning in depressed women with a history of sexual abuse.

Participants in this study will undergo a two-part screening interview at the Strong Adult Ambulatory Clinic. This screening will include both written questionnaires and face-to-face interviews regarding any experiences of sexual or physical abuse; suicidal thoughts; family relationships; and current attitudes, thoughts, or feelings. Participants who meet all criteria will then be randomly assigned to receive one of two treatments: interpersonal psychotherapy or individual psychotherapy, which is considered usual care. All treatment sessions will be held at the Strong Adult Ambulatory Clinic. Participants assigned to receive interpersonal psychotherapy will attend weekly 50-minute sessions with a therapist. Interpersonal psychotherapy will focus on current interpersonal stressors in daily life, such as difficulties in close relationships or at work. Treatment will also help participants examine the relationship between their mood changes and interpersonal problems. Participants assigned to receive individual psychotherapy will undergo cognitive-behavioral therapy, supportive counseling, or a combination of the two. Participants will work with their therapists to decide upon a treatment plan designed to help changes in mood and other difficulties in daily life. The number and length of treatment sessions for this group will be determined on an individual basis. For all participants, evaluations consisting of questionnaires similar to those from the initial screening will be completed at mid-treatment, post-treatment, and 3 months after treatment.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
Female
接受健康志愿者

入选标准

  • Meets DSM-IV criteria for unipolar major depressive disorder
  • History of childhood sexual abuse before the age of 18
  • Seeking outpatient psychotherapy treatment in a community mental health center

排除标准

  • Meets DSM-IV criteria for major depression with psychotic features, bipolar disorder, schizophrenia, or mental retardation
  • Active alcohol or substance abuse within 3 months of study entry date

结局指标

主要结局

Hamilton Rating Scale for Depression

时间窗: Measured at pre-treatment and Weeks 10, 24, and 36

Beck Depression Inventory

时间窗: Measured at pre-treatment and Weeks 10, 24, and 36

Structured Clinical Interview for DSM-IV Diagnoses

时间窗: Measured at pre-treatment and Weeks 10, 24, and 36

次要结局

  • Social Adjustment Scale(Measured at pre-treatment and Weeks 10, 24, and 36)
  • Medical Outcomes Survey(Measured at pre-treatment and Weeks 10, 24, and 36)
  • Post Traumatic Stress Disorder (PTSD) Symptom Scale(Measured at pre-treatment and Weeks 10, 24, and 36)

研究者

申办方类型
Other

研究点 (2)

Loading locations...

相似试验