Acellular Fish Skin Graft (FSG) vs Split-Thickness Skin Graft (STSG) for oral cavity defects after surgery in Oral Cavity Cancer: Randomized Clinical Trial

Phase 3

Recruiting

• Conditions: Fish Skin Graft, Oral Cavity, Cancer; CA Oral Cavity (stage T1,2 and 3) planned for Surgery

• Registration Number: TCTR20240512005
• Lead Sponsor: Ratchadapisek Research Funds Type I (Faculty of Medicine)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-05-12
• Last Update Posted: 19 August 2024
• Study Completion: 2025-12-31

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

1.Age > 18 years old, 2. CA Oral Cavity (stage T1,2 and 3) planned for Surgery at King Chulalongkorn Memorial Hospital / National Cancer Institute, 3.
Defect site area < 50 % of tongue or diameter less than 5 cm and possible to do reconstruction with FSG/STSG

Exclusion Criteria

1.Histoy Fish allergy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Inflammatory Proliferative Remodeling (IPR) Scale : IPR Scale day 5, day 14, 6 weeks scale

Secondary Outcome Measures

Name	Time	Method
HN-QOL day5, day14, 6 weeks questionnaire