Ultrasound-guided Modified Transversus Thoracic Muscle Plane Block and Erector Spinal Muscle Plane Block in Heart Valve Replacement Surgery With Median Incision
Trial Snapshot
- Phase
- Not Applicable
- Status
- Recruiting
- Sponsor
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- Heart beats
Study Overview
Brief Summary
Sternum midline incision can offer better view under open-heart surgery and bigger operating space, and therefore it has been widely used in most cardiac surgery. If an event of urgency occurs, it takes on a more important role than infrasternal small incision. However, sternum midline incision may cause serious pain and aggravates stress response, and therefore patients are often reluctant to cooperate to cough which exerts adverse effect on postoperative rehabilitation, and even causes serious complications such as pulmonary inflammation, myocardial infarction and heart failure. Thus, the relief of pain and better perioperative analgesia are very important for these patients. Transversus thoracic muscle plane(TTMP) block and erector spinal muscle plane(ESP) block are used in open heart surgery currently, and they can provide good analgesia. This study aimed to investigate the hemodynamic stability, total amount of analgesic use, perioperative pain, stress response, postoperative complication and recovery in patients receiving TMP and ESP.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Other
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 75 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •patients (18-75 years) with BMI at 18-25 kg/m2, ASA Ⅱ- Ⅲ and NYHA Ⅱ-Ⅲ who scheduled to undergo mitral valve or aortic valve replacement surgery.
Exclusion Criteria
- •a second operation, preoperative ejection fraction (EF) < 40%, complicated coronary heart disease, intra-aortic balloon counterpulsation (IABP) support, psychiatric abnormalities, history of allergy to anesthetic drugs, liver or kidney dysfunction, coagulation abnormality, endocrine system diseases and metabolic diseases.
Arms & Interventions
General anesthesia only (G) group
Transversus thoracic muscle plane block (T) group
Intervention: Transversus thoracic muscle plane block or Erector spinal plane block (Procedure)
Erector spinal plane block (E) group
Intervention: Transversus thoracic muscle plane block or Erector spinal plane block (Procedure)
Outcomes
Primary Outcomes
Heart beats
Time Frame: steel wire pulling (T6)
the number of times each minute that heart beats
Mean arterial pressure
Time Frame: steel wire pulling (T6)
an average blood pressure in an individual during a single cardiac cycle
Mean arterial pressure
Time Frame: breast opening (T3)
an average blood pressure in an individual during a single cardiac cycle
Mean arterial pressure
Time Frame: entering the operating room (T0)
an average blood pressure in an individual during a single cardiac cycle
Mean arterial pressure
Time Frame: intubation (T1)
an average blood pressure in an individual during a single cardiac cycle
Mean arterial pressure
Time Frame: skin incision (T2)
an average blood pressure in an individual during a single cardiac cycle
Mean arterial pressure
Time Frame: sternal retractor placement (T4)
an average blood pressure in an individual during a single cardiac cycle
Mean arterial pressure
Time Frame: pericardium incision (T5)
an average blood pressure in an individual during a single cardiac cycle
Heart beats
Time Frame: entering the operating room (T0)
the number of times each minute that heart beats
Heart beats
Time Frame: intubation (T1)
the number of times each minute that heart beats
Heart beats
Time Frame: skin incision (T2)
the number of times each minute that heart beats
Heart beats
Time Frame: breast opening (T3)
the number of times each minute that heart beats
Heart beats
Time Frame: sternal retractor placement (T4)
the number of times each minute that heart beats
Heart beats
Time Frame: pericardium incision (T5)
the number of times each minute that heart beats
Secondary Outcomes
No secondary outcomes reported
Investigators
Le Yu
Clinicians
Shanghai East Hospital of Tongji University