Ultrasound-guided Modified Transversus Thoracic Muscle Plane Block and Erector Spinal Muscle Plane Block in Heart Valve Replacement Surgery With Median Incision
- Conditions
- Anesthesia
- Interventions
- Procedure: Transversus thoracic muscle plane block or Erector spinal plane block
- Registration Number
- NCT06469073
- Lead Sponsor
- Le Yu
- Brief Summary
Sternum midline incision can offer better view under open-heart surgery and bigger operating space, and therefore it has been widely used in most cardiac surgery. If an event of urgency occurs, it takes on a more important role than infrasternal small incision. However, sternum midline incision may cause serious pain and aggravates stress response, and therefore patients are often reluctant to cooperate to cough which exerts adverse effect on postoperative rehabilitation, and even causes serious complications such as pulmonary inflammation, myocardial infarction and heart failure. Thus, the relief of pain and better perioperative analgesia are very important for these patients. Transversus thoracic muscle plane(TTMP) block and erector spinal muscle plane(ESP) block are used in open heart surgery currently, and they can provide good analgesia. This study aimed to investigate the hemodynamic stability, total amount of analgesic use, perioperative pain, stress response, postoperative complication and recovery in patients receiving TMP and ESP.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 60
- patients (18-75 years) with BMI at 18-25 kg/m2, ASA Ⅱ- Ⅲ and NYHA Ⅱ-Ⅲ who scheduled to undergo mitral valve or aortic valve replacement surgery.
- a second operation, preoperative ejection fraction (EF) < 40%, complicated coronary heart disease, intra-aortic balloon counterpulsation (IABP) support, psychiatric abnormalities, history of allergy to anesthetic drugs, liver or kidney dysfunction, coagulation abnormality, endocrine system diseases and metabolic diseases.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Transversus thoracic muscle plane block (T) group Transversus thoracic muscle plane block or Erector spinal plane block - Erector spinal plane block (E) group Transversus thoracic muscle plane block or Erector spinal plane block -
- Primary Outcome Measures
Name Time Method Heart beats steel wire pulling (T6) the number of times each minute that heart beats
Mean arterial pressure steel wire pulling (T6) an average blood pressure in an individual during a single cardiac cycle
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Shanghai East Hospital of Tongji University
🇨🇳Shanghai, Shanghai, China