Verb processing and word learning in DLD: Diagnostic tests and neural correlates
- Conditions
- taalontwikkelingsstoornissen'developmental language disorder' and 'specific language impairment'
- Registration Number
- NL-OMON53457
- Lead Sponsor
- Rijksuniversiteit Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 100
Children with a developmental language disorder (DLD):
- 8 to 12 years of age
- Attend special education (cluster 2 education) permanently or remotely
- Diagnosed with DLD by a licensed professional
Typically developing children:
- 8 to 12 years of age
- Attending regular education
Children with DLD:
- History of neurodevelopmental disorders
- History of psychiatric illness
- Recent use (within 1 week) of any psychopharmaceutic drug
- Intellectual disability
- Severe articulatory difficulties
- Uncorrected vision or hearing impairment
Typically developing children:
- A diagnosis of DLD or suspected DLD
- History of neurodevelopmental disorders
- History of psychiatric illness
- Recent use (within 1 week) of any psychopharmaceutic drug
- Intellectual disability
- Severe articulatory difficulties
- Uncorrected vision or hearing impairment
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>For the primary objective 1, the main MRI parameters are cortical thickness and<br /><br>white matter integrity (mean diffusivity, radial diffusivity, and fractional<br /><br>anisotropy). The main behavioral parameters are the scores on the verbal<br /><br>learning tasks. For objectives 2 and 3, the main parameters are the scores on<br /><br>the newly developed tasks of the verb battery.</p><br>
- Secondary Outcome Measures
Name Time Method <p>Demographic information (age, gender, parental educational level,<br /><br>mono/bi/multilingual language background) and general language or cognitive<br /><br>information (nonverbal IQ, auditory discrimination, word reading with Eén<br /><br>Minuut Test (EMT) and non-word reading with Klepel test) will be summarized and<br /><br>reported using descriptive statistics.<br /><br>Furthermore, scores in the CCC-2-NL questionnaire will be used to signal if<br /><br>any of the children recruited for the TD group presents with a profile<br /><br>indicative of language impairment. If so, or if the nonverbal IQ scores are<br /><br>outside the normal range, those children*s data will not be included in the<br /><br>study. </p><br>