Dexmedetomidine instilled in urinary bladder for prevention of post-operative catheter relatedbladder discomfort in renal transplant patients.

Phase 4

• Conditions: Health Condition 1: N186- End stage renal disease

• Registration Number: CTRI/2023/08/056908
• Lead Sponsor: Sanjay Gandhi Postgraduate Institute of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 18 September 2023

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

End Stage Renal Disease patients about to undergo Renal Transplant Surgery.

Exclusion Criteria

Patients with history of outflow obstruction, transurethral resection of prostate for benign prostatic hyperplasia, history of bladder catheterization within last 6 months, re look Percutaneous Nephrolithotomy, Pre-existing percutaneous nephrostomy , overactive bladder (frequency >3 times in the night or >8 times in 24 h), morbid obesity, disturbance of the central nervous system, chemical substance abuse or any psychiatric disease.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Incidence of Cathedral Related Bladder Discomfort (CRBD) in each group.Timepoint: 2 hours post surgery

Secondary Outcome Measures

Name	Time	Method
Incidence of Cathedral Related Bladder Discomfort (CRBD) in each group.Timepoint: 0, 4, 12 & 24 hours post surgery.;Incidence of postoperative nausea vomiting (PONV)Timepoint: 0,2,4,12 & 24 hours post surgery;Severity of CRBDTimepoint: 0,2,4,12,and,24 hours post surgery.