Comparison of the effect of licorice extract, ketamine and magnesium sulfate on gargling before laryngoscopy and endotracheal intubation in the prevention of sore throat, hoarseness and cough

Phase 3

Recruiting

• Conditions: General anesthesia.; Other complications of anaesthesia; T88.5

• Registration Number: IRCT20141209020258N170
• Lead Sponsor: Arak University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 11 January 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 105

Inclusion Criteria

30 to 60 years
ASA class I and II
No history of sore throat before surgery
No history of head and neck surgery, especially throat
No history of drug use
No history of chronic housing use
Hypersensitivity to the drugs used in this study
No upper airway infection and cold
No mallampati more than 2
Lack of liver and kidney failure
No need to use NG-tube during surgery and up to 24 hours after surgery
The duration of surgery should not be less than 45 minutes and not more than 120 minutes

Exclusion Criteria

Patient dissatisfaction to continue attending the study
Observing blood during suctioning when the endotracheal tube is removed
For any reason, we have to do laryngoscopy twice in the patient
History of heart disease and high blood pressure

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Sore throat. Timepoint: In recovery, 2, 4, 8, 12 and 24 hours after surgery. Method of measurement: Visual Pain Questionnaire.;Cough. Timepoint: In recovery, 2, 4, 8, 12 and 24 hours after surgery. Method of measurement: Physical examination.;Hoarseness. Timepoint: In recovery, 2, 4, 8, 12 and 24 hours after surgery. Method of measurement: Physical examination.