Targeted screening for detection of group B Streptococcus among Thai pregnant women during intrapartum period by real-time PCR
Not yet recruiting
- Conditions
- Group B streptococcus in pregnant womenDetection rate, Group B Streptococcus (GBS), Pregnancy, Real-time PCR, Streptococcus agalactiae, Targeted screening
- Registration Number
- TCTR20210801003
- Lead Sponsor
- Chulalongkorn university
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Female
- Target Recruitment
- 174
Inclusion Criteria
1. 18-45 years old Thai pregnant women
2. Gestational age 35 weeks or more
3. One or more Risk factors as below
GA < 37 weeks
Membrane rupture >= 18 hours
Intrapartum fever >= 38 o C
Teenage pregnancy
Previous vaginal delivery
Smoking during pregnancy
4. Giving consent
Exclusion Criteria
1.Previous child invasive GBS disease
2. Expected delivery within 4 hours
3. Indicated cesarean section
4. Vaginal bleeding due to placenta previa or placental abruption
5. Antibiotic use within 2 weeks before collecting sample
6. use any suppositories and creams within one week before sampling
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Detection rate When finished process of laboratory Detection rate , percentage
- Secondary Outcome Measures
Name Time Method Turnaround time When the laboratory finished Record turnaround time,Cost-effectiveness Within 6 days after birth Compare direct cost and EOGBS prevention,GBS detection between different risk factors group End of data collection Comparison of detection