se of the digital flicker test in patients with neuritis nervi optici and differential-diagnostically important diseases and investigation of the pathophysiology of the darkness enhancement phenomeno

Recruiting

• Conditions: H46; H47; C71; H30; H35; Optic neuritis; Other disorders of optic [2nd] nerve and visual pathways; Malignant neoplasm of brain; Chorioretinal inflammation; Other retinal disorders

• Registration Number: DRKS00031081
• Lead Sponsor: Forschungseinheit für Visuelle Rehabilitation, Department für Augenheilkunde, Universitätsklinikum Tübingen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-01-24
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Unilateral acute or subacute visual loss with or without optic disc changes.

Exclusion Criteria

Epilepsy, visual field defects of other etiology, visual acuity < 0.05 decimal.

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Determination of the Specificity and Sensitivity of the Digital Flicker Test (DFT)

Secondary Outcome Measures

Name	Time	Method
Investigation of the darkness enhancement phenomenon by selective stimulation of retinal ON- and OFF- center neurons in patients with neuritis nervi optici and ocularly healthy subjects